Publications by authors named "Renee Girens"
The role of taurine in the treatment of congestive heart failure (CHF) in dogs without systemic deficiency is unexplored. Taurine might have beneficial cardiac effects aside from deficit replacement. We hypothesized that oral taurine supplementation administered to dogs with naturally-occurring CHF would suppress the renin-angiotensin aldosterone system (RAAS).
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- Recent studies focused on dogs with diet-associated dilated cardiomyopathy (daDCM), highlighting the need for research across various breeds.
- The study evaluated 60 dogs with DCM (majority on nontraditional diets) and 16 dogs with subclinical cardiac abnormalities (SCA), measuring changes in their heart health over time after diet modifications.
- Results showed that while there were minimal initial differences in taurine levels, dogs on nontraditional diets experienced noticeable improvements in heart function after dietary changes, indicating the potential benefits of diet on cardiac health in these dogs.*
Background: Body surface area (BSA) can reflect metabolic rate that might normalize dosing of chemotherapeutics across widely variable weights within a species. The current BSA formula for dogs lacks height, length, and body condition.
Hypothesis: Computed tomography (CT) imaging will allow inclusion of morphometric variables in allometric modeling of BSA in dogs resulting in an improved formula for BSA estimation.
Physical activity has long been hypothesized to influence the risk and pathology of Alzheimer's disease. However, the amount of physical activity necessary for these benefits is unclear. We examined the effects of three months of low and high intensity exercise training on soluble Aβ40 and Aβ42 levels in extracellular enriched fractions from the cortex and hippocampus of young Tg2576 mice.
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