Publications by authors named "Renee Barry"
To evaluate the effects of preoperative oral diazepam on the postoperative course of patients undergoing primary augmentation mammoplasty in an outpatient surgical center. A retrospective review was conducted of 189 patients undergoing primary breast augmentation at an outpatient surgical center from 2012 to 2015. Patients receiving same-day premedication with oral diazepam were compared with a control group without premedication.
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- A study evaluated 328 patients with hormone receptor-positive, HER2/neu-negative breast cancer, consisting of 34.8% African American (AA) and 65.2% White American (WA) participants.
- The average age of patients was 60 years, with similar tumor sizes between AA (1.6 cm) and WA (1.7 cm), although AA had a higher average BMI (33 vs. 29.8).
- Distant recurrence rates were low for both groups (1.0% for AA and 1.6% for WA), indicating that the recurrence score (RS) utility is comparable between AA and WA patients, despite no significant differences in chemotherapy delivery.
GLI transport to the primary cilium and nucleus is required for proper Hedgehog (HH) signaling; however, the mechanisms that mediate these trafficking events are poorly understood. Kinesin-2 motor proteins regulate ciliary transport of cargo, yet their role in GLI protein function remains unexplored. To examine a role for the heterotrimeric KIF3A-KIF3B-KAP3 kinesin-2 motor complex in regulating GLI activity, we performed a series of structure-function analyses using biochemical, cell signaling and in vivo approaches that define novel specific interactions between GLI proteins and two components of this complex, KAP3 and KIF3A.
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