A fast in silico model for preoperative risk assessment of paravalvular leakage.

In silico simulations can be used to evaluate and optimize the safety, quality, efficacy and applicability of medical devices. Furthermore, in silico modeling is a powerful tool in therapy planning to optimally tailor treatment for each patient. For this purpose, a workflow to perform fast preoperative risk assessment of paravalvular leakage (PVL) after transcatheter aortic valve replacement (TAVR) is presented in this paper.

Computational modeling of braided venous stents - Effect of design features and device-tissue interaction on stent performance.

Designing venous stents with desired properties is challenging due to the partly conflicting performance criteria, e.g., enhancing flexibility may be at odds with increasing patency.