Family History of Nonsyndromic Orofacial Clefts: A Brazilian Multicenter Study.

Objective: To summarize the evidence on the relationship between hereditary family history and nonsyndromic orofacial clefts (NSOC) in patients from various Brazilian states.

Methods: This cross-sectional multicenter study was conducted at six specialized orofacial cleft services across different regions of Brazil. The sample consisted of 1899 patients with NSOC, including cleft lip only (NSCLO), cleft palate only (NSCPO), and cleft lip and palate (NSCLP).

Tooth Anomalies in Patients With Nonsyndromic Orofacial Cleft: A Systematic Review and Meta-Analysis.

Objective: To evaluate the frequency of tooth anomalies (TA) in the deciduous and permanent dentition of patients with nonsyndromic orofacial clefts (NSOC), both inside and outside the cleft area.

Methods: The following databases were searched for the relevant literature: Cochrane, OVID, SciELO, Embase, Livivo, PubMed, Scopus, and Web of Science. The risk of bias was analyzed using the Joanna Briggs Institute.

Taxonomical and biological notes on Argentoleon irrigatus (Gerstaecker) (Neuroptera: Myrmeleontidae).

Argentoleon irrigatus (Gerstaecker), is a common antlion species, but with sparse figures and incomplete location records in the literature, whose genitalia and larvae remained undescribed. Herein, the adults are redescribed and immatures (larvae and pupa) are described for the first time, providing images of internal and external characters, including both male and female genitalia. The examination and illustration of these characters allowed us to better understand the position and the limits of the genus Argentoleon Stange, within the tribe Brachynemurini, including the differentiation of the larval stages of the closely related genus Austroleon Banks.

Can microplastic contamination affect the wing morphology and wingbeat frequency of Aedes aegypti (Diptera: Culicidae) mosquitoes?

Microplastics (MPs) are increasingly widespread in the environment, which raises questions about their potential effects at different biological levels. It is essential to assess the impacts on biodiversity, and it is also crucial to understand whether the presence of MPs can interfere with the biological traits of species of relevance in public health. Considering that the life-history traits of mosquitoes, such as size and the wingbeat frequency (WBF), are related to its vector competence, here, we study the effects of 10 particles L (as expected concentration of MPs on the environment, using the polyethylene type) on WBF, as well as wing morphology, testing the Culicidae species found across all continents, Aedes aegypti, as an indicator.

Review of the Brazilian species of the genus Climaciella Enderlein (Neuroptera: Mantispidae), with the description of two new species.

Climaciella Enderlein is a genus of the family Mantispidae (Neuroptera) restricted to the New World with records ranging from southern Canada to northern Argentina. The genus is currently represented by 12 valid species, three of them with records from Brazil: C. amapaensis Penny, C.

Assessing the Efficacy of Submental Liposuction Association in Orthognathic Surgery: A Systematic Review.

Purpose: Despite the vast literature on submental liposuction, there are few studies describing its simultaneous association in orthognathic surgery. This systematic review aimed to evaluate the available evidence on the effectiveness of the combination between the 2 techniques.

Methods: This study followed the Preferred Reporting Items for Systematic reviews and Meta-Analyses checklist and used a comprehensive literature search across 7 databases.

Frequency of Oral Lesions, Olfactory, and Gustatory Disorders and Xerostomia in Patients with COVID-19.

COVID-19, a respiratory illness with a global impact on millions, has recently been linked to manifestations affecting various bodily systems, including the oral cavity. Studies highlight oral issues, like ulcers, blisters, and white patches, alongside olfactory and gustatory dysfunction, influencing an individual's quality of life. In this context, our study aimed to assess the frequency of oral lesions, olfactory and gustatory disorders, and xerostomia resulting from COVID-19.

A rare LMNA missense mutation causing a severe phenotype of mandibuloacral dysplasia type A: a case report.

Objective: To report the case of a girl presenting a severe phenotype of mandibuloacral dysplasia type A (MADA) characterized by prominent osteolytic changes and ectodermal defects, associated with a rare homozygous LMNA missense mutation (c.1579C>T).

Case Description: A 6-year-old girl was evaluated during hospitalization exhibiting the following dysmorphic signs: subtotal alopecia, dysmorphic facies with prominent eyes, marked micrognathia and retrognathia, small beaked nose, teeth crowding and thin lips, generalized lipodystrophy, narrow and sloping shoulders, generalized joint stiffness and bone reabsorption in the terminal phalanges.

A camouflaged diversity: taxonomic revision of the thorny lacewing subfamily Symphrasinae (Neuroptera, Rhachiberothidae).

Species of the thorny lacewing subfamily Symphrasinae (Neuroptera: Rhachiberothidae) are revised. Prior to this work, 42 species were known in the genera Navás, 1909, Navás, 1928, and Westwood, 1852. Herein, the number of species is increased to 60, 23 of which are newly described.

Oligodontia in the Clinical Spectrum of Syndromes: A Systematic Review.

The aim of this systematic review was to describe the clinical and genetic features of syndromes showing oligodontia as a sign. The review was performed according to the PRISMA 2020 checklist guidelines, and the search was conducted using PubMed, Scopus, Lilacs, Web of science, Livivo, and EMBASE and supplemented by a gray literature search on Google Scholar and ProQuest, applying key terms relevant to the research questions. The systematic review identified 47 types of syndromes in 83 studies, and the most common was hypohidrotic ectodermal dysplasia, which was reported in 24 patients in 22 studies.

Comparison between sex and polymorphisms on FKBP5: perception of quality of life in non-syndromic patients. A cross-sectional study.

This study aimed to compare factors that influence perception of quality of life (QoL) in patients scheduled for orthognathic surgery. This was a cross-sectional study with 91 participants from two universities in Curitiba. The orthognathic quality of life questionnaire (OQLQ) was used to assess patients' perceptions of their QoL.

Benefits of Coronectomy in Lower Third Molar Surgery: A Systematic Review and Meta-analysis.

Purpose: The purpose of this study was to measure and compare coronectomy versus extraction in patients at increased risk for inferior alveolar nerve (IAN) injuries associated with third molar removal in terms of IAN injury and other complications.

Methods: The review adhered to the Preferred Reporting Items for Systematic Reviews and Meta-analyses checklist. We conducted a comprehensive literature search across six databases and the gray literature from July 15 to August 01, 2022.

Isolated nonsyndromic cleft palate: multicenter epidemiological study in the Brazil.

Background: Nonsyndromic orofacial clefts (NSOC) are the craniofacial most common congenital malformations. There are evidences that the nonsyndromic cleft palate (NSCP) development differs from other NSOC. However, most of the publications treat NSCP without considering that information.

Ethnic Differences in the Brazilian Population Influence the Impact of Genetic Variants on Susceptibility of Nonsyndromic Orofacial Clefts.

Objective: The study evaluated the association of tag-SNPs and SNP-SNP interactions involving genes active by BMP4 pathway during craniofacial development in the susceptibility of nonsyndromic orofacial clefts (NSOC) in the Brazilian population.

Design: Case-control study.

Setting: Brazilian Oral Cleft Group.

Overexpression of heat-shock protein 47 impacts survival of patients with oral squamous cell carcinoma.

Background: The expression of heat-shock protein 47 (HSP47) has been linked to collagen synthesis control and implicated in fibrotic disorders, but more recent studies have demonstrated its role in solid tumors. In this study, we explored the prognostic impact of HSP47 in oral squamous cell carcinomas (OSCC) and determined the in vitro effects of its loss-of-function on viability, proliferation, migration, invasion, and resistance to cisplatin of OSCC cells.

Methods: The HSP47 expression in tumor samples was assessed by immunohistochemistry in two independent cohorts totaling 339 patients with OSCC, and protein levels were associated with clinicopathological features and survival outcomes.

A new species of Bittacus Latreille (Mecoptera: Bittacidae) from the Andean-Amazonian foothills, Caquetá, Colombia.

A new hangingfly species, Bittacus rafaeli sp. nov. (Mecoptera: Bittacidae), is herein described and illustrated, based on two specimens from the municipality of El Doncello, Caquetá, Colombia.

Associations between Anxiety, Depression, Chronic Pain and Oral Health-Related Quality of Life, Happiness, and Polymorphisms in Adolescents' Genes.

Adolescence is marked by changes and vulnerability to the emergence of psychological problems. This study aimed to investigate associations between anxiety/depression/chronic pain and oral health-related quality of life (OHRQoL)/happiness/polymorphisms in the , and genes in Brazilian adolescents. A cross-sectional study was conducted with ninety adolescents 13 to 18 years.

Stress induced phosphoprotein 1 overexpression controls proliferation, migration and invasion and is associated with poor survival in oral squamous cell carcinoma.

Objective: Although there have been remarkable achievements in the molecular landscape of oral squamous cell carcinoma (OSCC) in recent years, bringing advances in the understanding of its pathogenesis, development and progression, little has been applied in the prognosis and choosing the optimal treatment. In this study, we explored the influence of the stress induced phosphoprotein 1 (STIP1), which is frequently reported to be highly expressed in many cancers, in OSCCs.

Methods: STIP1 expression was assessed in the TCGA database and in two independent cohorts by immunohistochemistry.

Brazilian Multiethnic Association Study of Genetic Variant Interactions among , and in the Risk of Nonsyndromic Cleft Lip with or without Cleft Palate.

Associations of (cysteine-rich secretory protein LCCL domain containing 2) and genes belonging to its activation pathway, including (Fos proto-oncogene), (caspase 8) and with nonsyndromic orofacial cleft risk, have been reported, but the results are yet unclear. The aim of this study was to evaluate single nucleotide polymorphisms (SNPs) in , and and to determine their SNP-SNP interactions with variants in the risk of nonsyndromic cleft lip with or without cleft palate (NSCL±P) in the Brazilian population. The SNPs rs1046117 (), rs3769825 () and rs243836 () were genotyped using TaqMan allelic discrimination assays in a case-control sample containing 801 NSCL±P patients (233 nonsyndromic cleft lip only (NSCLO) and 568 nonsyndromic cleft lip and palate (NSCLP)) and 881 healthy controls via logistic regression analysis adjusted for the effects of sex and genomic ancestry proportions with a multiple comparison value set at ≤0.