Publications by authors named "Renato Jorge Alves"

Article Synopsis
  • * Symptoms of CTX include cataracts, gallstones, diarrhea, and early heart disease, but presentation can vary widely among patients.
  • * The report discusses two cases with CTX where patients had genetic mutations but did not have elevated cholesterol levels in the blood or tendons, suggesting CTX may involve more genetic variability than previously understood.
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Article Synopsis
  • - GPIHBP1 is crucial for the function of lipoprotein lipase (LPL), and mutations in the GPIHBP1 gene can cause serious health issues like hypertriglyceridemia and pancreatitis.
  • - This study identifies a new homozygous mutation in the GPIHBP1 gene found in twelve patients from Brazil, affecting how the gene processes and leading to significant health implications.
  • - The mutation, located in a critical splicing site, results in severe hypertriglyceridemia and low HDL levels in patients, with a notable percentage having a history of acute pancreatitis, indicating a potential founder effect in this population.
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Background: [Corrected] Atrial fibrillation is a common complication after cardiac surgery. The previous use of statins may reduce the incidence of this arrhythmia.

Objective: To evaluate whether the chronic and regular use of statins, for a period of six months, prevents atrial fibrillation after elective cardiac surgery.

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We evaluated the case of a patient with Papillary Fibroelastoma (PFE) that presented embolization to the upper right limb. The patient was submitted to percutaneous embolectomy, with fragment removal. The diagnosis was confirmed by transthoracic echocardiogram and anatomopathological analysis of the fragment.

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To evaluate arrhythmogenic risk factors associated with greater incidence of postoperative atrial fibrillation (POAF) in patients undergoing cardiac surgery (CABG and/or valvular surgery) in order to identify those more prone to the development of this arrhythmia for possible chemoprophylaxis. Sixty-six patients who underwent elective cardiac surgery were assessed. The following risk factors for the development of POAF were correlated: advanced age, valvular heart disease (VHD), left atrial (LA) enlargement, left ventricular dysfunction (LVD), electrolyte imbalance (EI), previous CABG, prior use and withdrawal of beta-blockers (BB) and/or digitalis 24 hours before surgery).

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Objective: To assess if prophylaxis with moderate doses of amiodarone in the postoperative period of cardiac surgery (coronary artery bypass grafting and/or valve surgery), reduces the incidence of atrial fibrillation in patients with high risk for developing this arrhythmia.

Methods: A randomized and prospective clinical study involving 68 patients who underwent elective cardiac surgery. Mean age was 64 years and 59% of participants were males.

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