A framework for developing a real-time lake phytoplankton forecasting system to support water quality management in the face of global change.

Phytoplankton blooms create harmful toxins, scums, and taste and odor compounds and thus pose a major risk to drinking water safety. Climate and land use change are increasing the frequency and severity of blooms, motivating the development of new approaches for preemptive, rather than reactive, water management. While several real-time phytoplankton forecasts have been developed to date, none are both automated and quantify uncertainty in their predictions, which is critical for manager use.

Model development, testing and experimentation in a CyberWorkstation for Brain-Machine Interface research.

The CyberWorkstation (CW) is an advanced cyber-infrastructure for Brain-Machine Interface (BMI) research. It allows the development, configuration and execution of BMI computational models using high-performance computing resources. The CW's concept is implemented using a software structure in which an "experiment engine" is used to coordinate all software modules needed to capture, communicate and process brain signals and motor-control commands.

Cyber-workstation for computational neuroscience.

A Cyber-Workstation (CW) to study in vivo, real-time interactions between computational models and large-scale brain subsystems during behavioral experiments has been designed and implemented. The design philosophy seeks to directly link the in vivo neurophysiology laboratory with scalable computing resources to enable more sophisticated computational neuroscience investigation. The architecture designed here allows scientists to develop new models and integrate them with existing models (e.

BMI cyberworkstation: enabling dynamic data-driven brain-machine interface research through cyberinfrastructure.

Dynamic data-driven brain-machine interfaces (DDDBMI) have great potential to advance the understanding of neural systems and improve the design of brain-inspired rehabilitative systems. This paper presents a novel cyberinfrastructure that couples in vivo neurophysiology experimentation with massive computational resources to provide seamless and efficient support of DDDBMI research. Closed-loop experiments can be conducted with in vivo data acquisition, reliable network transfer, parallel model computation, and real-time robot control.

Architecture and performance of a Grid-enabled lookup-based biomedical optimization application: light scattering spectroscopy.

This paper presents a case study of a Grid-enabled implementation of light scattering spectroscopy (LSS). The LSS technique allows noninvasive detection of precancerous changes in human epithelium, differentiating from traditional biopsies by allowing in vivo diagnosis of tissue samples and quantitative analyses of parameters related to cancerous changes via numerical techniques. This paper describes the architecture of GridLSS and its integration with a Web-based Grid computing portal.