Prevalence of c-myc expression in breast lesions associated with microcalcifications detected by routine mammography.

Context And Objective: Genetic abnormalities in cell proliferation-regulating genes have been described in premalignant lesions. The aims here were to evaluate c-myc protein expression in non-palpable breast lesions associated with microcalcifications, detected by screening mammography, and to compare these results with histopathological, clinical and epidemiological variables.

Design And Setting: Analytical cross-sectional study, with retrospective data collection, in a university hospital in São Paulo.