Publications by authors named "Renato Cesar Caetano"
Aspergillus fumigatus is a saprophytic fungus as well as a so-called opportunist pathogen. Its biochemical potential and enzyme production justify intensive studies about biomolecules secreted by this microorganism. We describe the alkaline serine peptidase production, with optimum activity at 50°C and a pH of 7.
View Article and Find Full Text PDFCell cycle arrest evidence, parasiticidal and bactericidal properties induced by L-amino acid oxidase from Bothrops atrox snake venom.
Raquel de Melo Alves Paiva Raquel de Freitas Figueiredo Gilmara Ausech Antonucci Helder Henrique Paiva Maria de Lourdes Pires Bianchi Renato Cesar Caetano
Biochimie
May 2011
Article Synopsis
- The article discusses an l-amino acid oxidase (BatroxLAAO) from Bothrops atrox snake venom, which has shown antiprotozoal activity against Trypanosoma cruzi and various Leishmania species, with its effectiveness linked to H2O2 production.
- BatroxLAAO also possesses antibacterial properties against different bacteria and induces apoptosis in certain human cell lines, leading to cell cycle arrest in the G0/G1 phase and inhibiting cell proliferation.
- This enzyme is highlighted as a significant subject for understanding snake venom mechanisms and holds potential for therapeutic applications.