Publications by authors named "Renato Casanova-Mendoza"

Article Synopsis
  • The study evaluated the desensitization and re-desensitization of antituberculosis drugs (ATDs) in patients with DRESS syndrome, aiming to increase cure rates for tuberculosis despite potential severe drug reactions.
  • Conducting a retrospective case series from 2021 to 2023, the researchers applied a specialized protocol on 18 patients, achieving a 72.2% success rate in managing DRESS syndrome related to ATDs.
  • Findings showed that rifampicin, isoniazid, and pyrazinamide were the main culprits of DRESS syndrome symptoms such as fever and rash, with the study's algorithm proving to be a safe and effective way to treat
View Article and Find Full Text PDF

Tuberculosis (TB) poses a significant global public health challenge, particularly in developing countries. Over the years, scientific research has played a pivotal role in addressing this disease. In this study, we aimed to analyze and outline the trends in scientific output on TB and identify research priorities in Latin America (LA) from 1990 to 2021.

View Article and Find Full Text PDF

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare, life-threatening adverse reaction caused by certain medications. Clinical findings usually include rash, fever, lymphadenopathy, and eosinophilia, and in some cases, they may affect major organs. This reaction caused by antituberculosis (TB) medication poses a public health risk due to treatment discontinuation, adherence, or success in cure.

View Article and Find Full Text PDF

Bullous lung disease caused by tuberculosis is rare, and complications have a poor prognosis with uncertain pathophysiologic mechanisms. We describe a 29-year-old male patient who was admitted to the emergency department due to bilateral tension pneumothorax, which was complicated by bronchopleural fistula. This was managed with the placement of chest tubes, continuity of anti-TB drug treatment, and Heimlich valve placement.

View Article and Find Full Text PDF

Pulmonary lophomoniasis is a rare and life-threatening disease, most commonly reported across Asian and Latin American countries. Here, we have reported two cases of pulmonary lophomoniasis presenting with atypical manifestations. Case #1 represents a 19-year-old male patient with clinical characteristics suggestive of tuberculosis, presenting with hemoptysis and receiving antituberculosis treatment.

View Article and Find Full Text PDF

This document constitutes a summary of the clinical practice guidelines (CPGs) prepared at the initiative of the Latin American Thoracic Society (ALAT). Due to new evidence in the treatment of severe asthma, it was agreed to select six clinical questions, and the corresponding recommendations are provided herein. After considering the quality of the evidence, the balance between desirable and undesirable impacts and the feasibility and acceptance of procedures, the following recommendations were established.

View Article and Find Full Text PDF