Publications by authors named "Renate J Bosma"
Article Synopsis
- A 39-year-old woman diagnosed with relapsing nephrotic syndrome was found to have cryofibrinogen and a monoclonal immunoglobulin (M-protein) in her blood, indicating monoclonal gammopathy related to kidney issues.
- Initial immunosuppressive treatment led to temporary improvement, but after her condition relapsed, she underwent more intensive therapy, including stem cell transplantation, which again provided temporary relief.
- Subsequent experiments revealed that the cryoactivity was dependent on the M-protein, suggesting that cryofibrinogenemia is linked to this protein and should be associated with monoclonal gammopathy of renal significance.
Creatinine-based equations are available to estimate GFR. After renal transplantation body composition usually changes, thus specific validation is required for transplant recipients. Nine equations were compared with iothalamate glomerular filtration rate (GFR) at 1 year after transplantation in 798 recipients.
View Article and Find Full Text PDFBackground: Weight excess is associated with increased renal risk. Data in overt obesity suggest a role for altered renal hemodynamics. Whether body mass index (BMI) is also relevant to renal function in non-obese subjects is unknown.
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