Publications by authors named "Renata Wachnicka-Truty"

Article Synopsis
  • Current guidelines do not require transesophageal echocardiography (TEE) for well-anticoagulated patients before catheter ablation (CA) for atrial arrhythmias, but clinical practice often differs.
  • This study analyzed data from the LATTEE registry to find echocardiographic parameters that can effectively predict the absence of left atrial thrombus (LAT) in patients, which would help skip unnecessary TEE procedures.
  • Key echocardiographic criteria, such as a left ventricular ejection fraction over 65% and specific left atrial measurements, showed 100% sensitivity for identifying LAT-free patients, potentially allowing 35% of patients to avoid TEE before CA.
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Article Synopsis
  • Transoesophageal echocardiography (TOE) is typically used to check for left atrial appendage thrombus (LAT) before procedures like cardioversion, but it can be uncomfortable for patients on long-term anticoagulants.
  • A machine learning model called LAT-AI was developed to predict the presence of LAT using data from a large patient registry involving both training and external testing cohorts.
  • The study found that LAT-AI performed better than conventional methods in predicting LAT, and implementing its protocol could help 40% of patients on anticoagulation avoid unnecessary TOE procedures.
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Introduction: The left atrium appendage thrombus (LAAT) formation is a complex process. A CHADS-VASc scale is an established tool for determining the thromboembolic risk and initiation of anticoagulation treatment in patients with atrial fibrillation or flutter (AF/AFL). We aimed to identify whether any transthoracic echocardiography (TTE) parameters could have an additional impact on LAAT detection.

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Background: Our aim was to assess the characteristics and to identify predictors of left atrial thrombus (LAT) in patients under age 65 with atrial fibrillation (AF) or atrial flutter (AFl).

Methods: We conducted a subanalysis of a multicenter, prospective, observational study [the LATTEE registry]. Consecutive AF/AFl patients referred for cardioversion or ablation were enrolled.

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An increased body mass index (BMI) is associated with a higher incidence of atrial fibrillation (AF) and a higher risk of thromboembolic complications in AF patients. The aim of this study was to investigate the effect of BMI on the risk of left atrial thrombi (LATs) in patients with nonvalvular AF/atrial flutter (AFl) (NV AF/AFl). Patients diagnosed with NVAF/AFl (between November 2018 and May 2020) were selected from the multicenter, prospective, observational Left Atrial Thrombus on Transesophageal Echocardiography (LATTEE) registry that included AF/AFl patients referred for cardioversion or ablation followed by transesophageal echocardiography.

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Aims: The aim of the study was to evaluate the prevalence of left atrial thrombus (LAT) on transoesophageal echocardiography (TOE) in patients with atrial fibrillation or atrial flutter (AF/AFl) with reference to the presence of heart failure (HF) and its subtypes.

Methods And Results: The research is a sub-study of the multicentre, prospective, observational Left Atrial Thrombus on Transoesophageal Echocardiography (LATTEE) registry, which comprised 3109 consecutive patients with AF/AFl undergoing TOE prior to direct current cardioversion or catheter ablation. TOE parameters, including presence of LAT, were compared between patients with and without HF and across different subtypes of HF, including HF with preserved (HFpEF), mid-range (HFmrEF), and reduced ejection fraction (HFrEF).

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Background: Atrial fibrillation (AF) and flutter (AFl) increase the risk of thromboembolism. The aim of the study was to assess the prevalence of left atrial thrombus (LAT) in AF/AFl in relation to oral anticoagulation (OAC). Methods: LATTEE (NCT03591627) was a multicenter, prospective, observational study enrolling consecutive patients with AF/AFl referred for transesophageal echocardiography before cardioversion or ablation.

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