Publications by authors named "Renata Tj Fazoli"
Drugs Context
August 2024
Article Synopsis
- The discovery of RNA interference in 1998 led to the creation of siRNA drugs, including Patisiran, which targets a rare genetic disease called hereditary transthyretin amyloidosis.
- Additional siRNA medications like Givosiran and inclisiran have shown positive results in treating genetic disorders and hypercholesterolemia, respectively, with ongoing research on their broader health impacts.
- New siRNA therapies are being explored for cardiovascular conditions, aiming to reduce risk factors like lipoprotein(a) and angiotensinogen levels, with a hopeful outlook for their effectiveness in improving heart health and long-term safety in larger populations.
