Background: Eccentric instruments have been proposed as more effective and less time-consuming for endodontic instrumentation.
Aim: To compare biomechanical outcomes of different instrumentation systems and time undertaken for instrumentation in resin prototypes.
Design: Sixty standardized prototypes of mandibular second primary molars were instrumented according to the following systems: K-files, ProTaper Next (PTN), XP-endo Shaper (XPS), XP-endo Finisher (XPF), XP-Clean (XPC), and Sequence Baby File (SBF; n = 10/each).