Publications by authors named "Renata Galvao de Azevedo"

Nanocapsules provide selective delivery and increase the bioavailability of bioactive compounds. In this study, we examined the anticancer and immunomodulatory potential of (crajiru) extract encapsulated in nanocapsules targeting myeloid leukemias. Nanocapsules containing crajiru (nanocapsules-CRJ) were prepared via interfacial polymer deposition and solvent displacement.

View Article and Find Full Text PDF

() is a prominent plant used in Moroccan traditional medicine. This study investigated the phenolic composition and the anti-inflammatory, the hepatoprotective, and the anticancer activities of a hydroethanolic extract of leaves and stems. Ultra-high-performance liquid chromatography identified the phenolic profile.

View Article and Find Full Text PDF
Article Synopsis
  • This study focused on a newly developed spiroindolone derivative and its potential as a cancer treatment, specifically for chronic leukemia.
  • The compound was tested on cancerous K562 cells and showed significant cytotoxic effects while causing minimal harm to normal cells.
  • Results indicated that the compound not only halted cancer cell growth by inducing G2/M cell cycle arrest but also boosted the production of important immune cytokines, suggesting its dual role as an anti-cancer and immunomodulatory agent.
View Article and Find Full Text PDF

(Guss.) is an important medicinal plant widely used in Morocco for various traditional purposes. Our work aimed to evaluate the phenolic composition, wound healing, antinociceptive, and anticancer activities of extracts.

View Article and Find Full Text PDF