Increased antinuclear (anti-Sm) antibodies in infertile patients with peritoneal endometriosis.

Objective: The aim of this study is to evaluate the intensity of five antibodies against extractable nuclear antigens (ENA: RNP, ScL-70, SS-B, SS-A, and Sm) in infertile patients with endometriosis.

Methods: We investigated infertile women with minimal/mild endometriosis (n=43) and fertile women (n=46).

Results: The intensity of immunoreactions was also similar for anti-RNP and anti-SS-A antibodies.

Transforming growth factor beta-1 (TGF-β1) expression in patients with adenomyosis.

Objective: To compare Transforming growth factor beta-1 (TGF-β1) expression in patients with and without adenomyosis.

Methods: A prospective design was performed including 49 patients submitted to hysterectomy. Immunohistochemistry was performed on anatomopathological samples staged in paraffin blocks from patients with and without adenomyosis.