Publications by authors named "Renata F F Moraes"

Article Synopsis
  • The study observed a rise in community-acquired Clostridioides difficile infection (CA-CDI) in the past decade, prompting an investigation into its presence in domestic dogs in Rio de Janeiro.
  • Researchers collected and analyzed 90 stool samples from dogs, identifying C. difficile in 15.5% of them, with the majority showing positive results for harmful toxin genes.
  • Out of the isolated strains, some exhibited antibiotic resistance, particularly to metronidazole and vancomycin, and shared genetic traits with known epidemic strains, indicating a potential link between dogs and the spread of C. difficile.
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This prospective, blinded, randomized crossover study aimed to assess the anesthetic effects of the combination of 30 mg/kg ketamine and 2 mg/kg midazolam via intranasal (IN) or intramuscular (IM) routes in twelve domestic chickens. Physiological parameters (respiratory rate - RR, heart rate - HR, and cloacal temperature -Tºcloacal) were monitored throughout the experiment, along with recovery time and sedation level (S0: awake, no recumbency, responsive to stimuli; S1: blinking eyes, recumbency, relaxed, response to stimulus, mild movement; S2: open eyes, recumbency, relaxed, mild response to stimuli; S3: closed eyes, recumbency, relaxed, no movement). In the IM group, all birds reached S3, while in IN 5/12 reached S3, 4/12 reached at most S1, and 1/12 at most S2.

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Article Synopsis
  • Clostridioides difficile infections (CDI) are typically associated with hospitals but are increasingly appearing in community settings, with potential sources identified in animals and meat, suggesting zoonotic transmission.
  • This study aimed to isolate and characterize C. difficile strains from dogs at a veterinary clinic in Rio de Janeiro to better understand gastrointestinal disorders linked to these infections.
  • The research found that 20% of the dogs tested positive for toxigenic C. difficile strains, with some showing antibiotic resistance, but no significant morphological changes were observed in their intestinal pathology.
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