Publications by authors named "Renata Cougo Moraes"
Context: Uncaria tomentosa D.C. (Rubiaceae) has several biological activities, including activity against resistant Candida strains.
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- The study investigates the antitumor effects of Uncaria tomentosa, focusing on the influence of different alkaloid forms from its bark on bladder cancer cell lines T24 and RT4.
- Extracts were prepared and subjected to isomerization by heating, and analysis showed no significant differences in cytotoxicity between the original and isomerized alkaloid samples at various heating times.
- Specific alkaloids like mitraphylline and speciophylline were found to be more prone to isomerization, indicating that the conditions of the extraction and incubation play a crucial role in determining the alkaloid profile and their corresponding effects against cancer cells.