The impact of upright radiographs of midshaft clavicle fractures on treatment recommendations.

Clavicle fractures' treatment recommendations are based on displacement. The goal of this paper is to determine upright clavicle radiographs at initial presentation changes timing and method of treatment. Retrospective study in a level 1 trauma center.

AB5075, a Highly Virulent Isolate of Acinetobacter baumannii, as a Model Strain for the Evaluation of Pathogenesis and Antimicrobial Treatments.

Unlabelled: Acinetobacter baumannii is recognized as an emerging bacterial pathogen because of traits such as prolonged survival in a desiccated state, effective nosocomial transmission, and an inherent ability to acquire antibiotic resistance genes. A pressing need in the field of A. baumannii research is a suitable model strain that is representative of current clinical isolates, is highly virulent in established animal models, and can be genetically manipulated.

Failure and salvage of "INFIX" instrumentation for pelvic ring disruption in a morbidly obese patient.

Open-book pelvic fractures in the obese patient are accompanied by an increased risk of fixation failure. We report on the use of a recently described anterior subcutaneous pelvic internal fixator, the "INFIX" technique, in a morbidly obese patient. In this case, single and double rod constructs alone did not maintain adequate fixation due to the extreme forces in a morbidly obese patient.

Incisional negative pressure wound therapy after high-risk lower extremity fractures.

Objectives: To investigate negative pressure wound therapy (NPWT) to prevent wound dehiscence and infection after high-risk lower extremity trauma.

Design: Prospective randomized multicenter clinical trial.

Setting: Four Level I trauma centers.

Increasing vascularity to improve healing of a segmental defect of the rat femur.

Background: Segmental bone loss remains a challenging clinical problem. A frequent mitigating factor is inadequate blood supply. Small molecules that activate the hypoxia-inducible factor pathway can be used to stimulate angiogenesis.

The use of a biodegradable, load-bearing scaffold as a carrier for antibiotics in an infected open fracture model.

Objectives: Open fractures with bone loss are common, disabling injuries. Biodegradable, load-bearing scaffolds able to carry high concentrations of local antibiotics are an emerging technology to address these injuries. This study investigates the use of such scaffolds with gentamicin (along with bone morphogenetic protein) in an infected rat open fracture model to decrease osteomyelitis and promote fracture healing.

Quantitative analysis of growth factors from a second filter using the Reamer-Irrigator-Aspirator system: description of a novel technique.

Use of the Reamer-Irrigator-Aspirator (RIA) as a source of autogenous bone graft in the treatment of nonunions is increasing. We report on our novel technique of using a second filter containing beta-tricalcium phosphate (TCP) as a graft extender while using the RIA system. We also quantify growth factor concentrations in the collections from the TCP filter.

Subtrochanteric femur fracture after core decompression and placement of a tantalum strut for osteonecrosis of the femoral head.

Multiple treatment options have been described to treat osteonecrosis of the femoral head, all with the goal of slowing or reversing the disease process and preventing the need for arthroplasty in a young patient population. Core decompression of the femoral head to allow revascularization is a commonly used technique that can now be supplemented by placement of the Osteonecrosis Intervention Implant (Zimmer, Warsaw, Ind). It consists of a tantalum strut that acts as a buttress for the subchondral bone of the femoral head.

Negative pressure wound therapy after severe open fractures: a prospective randomized study.

Objectives: To evaluate the impact of negative pressure wound therapy (NPWT) after severe open fractures on deep infection.

Design: Prospective randomized study.

Setting: Academic level I trauma center.

Segmental bone regeneration using a load-bearing biodegradable carrier of bone morphogenetic protein-2.

Segmental defect regeneration has been a clinical challenge. Current tissue-engineering approach using porous biodegradable scaffolds to delivery osteogenic cells and growth factors demonstrated success in facilitating bone regeneration in these cases. However, due to the lack of mechanical property, the porous scaffolds were evaluated in non-load bearing area or were stabilized with stress-shielding devices (bone plate or external fixation).

Ultrasound produced by a conventional therapeutic ultrasound unit accelerates fracture repair.

Background And Purpose: A recent novel application of ultrasound therapy is the treatment of bone fractures. The aim of this study was to investigate the effect on fracture repair of ultrasound produced by a conventional therapeutic ultrasound unit as used by physical therapists.

Subjects And Methods: Bilateral midshaft femur fractures were created in 30 adult male Long-Evans rats.

Preliminary evaluation of a load-bearing BMP-2 carrier for segmental defect regeneration.

Large segmental defects in bones can result from tumor removal, massive trauma, congenital malformation, or non-union fractures. Such defects often are difficult to manage and require multiple-phase surgery to achieve adequate union and function. In this study, we propose a novel design of bone morphogenetic protein 2 (BMP-2) carrier for tissue engineering of segmental defect regeneration.

Effect of low molecular weight heparin on fracture healing in a stabilized rat femur fracture model.

The purpose of this study was to evaluate the effect of low molecular weight heparin (LMWH) on fracture healing in a standard stabilized rat femur fracture model. A closed, mid-diaphyseal transverse fracture was created in the right femur of Long-Evans rats after insertion of a 0.8-mm K-wire into the medullary canal.

Preliminary stabilization of the less invasive stabilization system.

We describe the use of a universal T-handle chuck to provide preliminary stabilization of the Less Invasive Stabilization System supracondylar femur implant and aiming device. This technique is helpful to maintain the position of the plate against the bone during intraoperative radiographs and initial screw insertion. Use of this simple technique may help avoid the problems that occur when the plate is positioned too far away from the lateral femoral cortex.

Snowmobile trauma: 10 years' experience at Manitoba's tertiary trauma centre.

Introduction: According to the literature, the increased recreational use of the snowmobile has resulted in an increasing number of musculoskeletal injuries. We wished to examine whether previously described risk factors continue to be associated with snowmobile trauma and to identify previously unrecognized risks and specific patterns of injury.

Methods: We carried out a chart review of all snowmobile-related injuries over a 10-year period at the Health Sciences Centre in Winnipeg, the only level 1 trauma centre serving the Province of Manitoba, with particular attention to the risk factors of suboptimal lighting, excessive speed and alcohol consumption.