Publications by authors named "Rena Fujishima"
Medical therapeutic options to prevent rupture of abdominal aortic aneurysm (AAA), a critical event, must be developed. Moreover, further understanding of the process of AAA development and rupture is crucial. Previous studies have revealed that aortic hypoperfusion can induce the development of AAA, and we successfully developed a hypoperfusion-induced AAA animal model.
View Article and Find Full Text PDFVisualization of Functional Food Factors by Matrix-Assisted Laser Desorption/Ionization Imaging Mass Spectrometry.
J Nutr Sci Vitaminol (Tokyo)
November 2022
Dietary habit is closely associated with healthspan. Functional food factors are key to maintaining a health metabolism in our bodies. Because functional food factors are main components to determine the quality of foods, many technologies have been established to analyze functional factors in foods.
View Article and Find Full Text PDFAbdominal aortic aneurysm (AAA) is an aortic disease in which the aortic diameter is ≥3.0 cm; if left untreated, the aortic wall continues to weaken, resulting in progressive dilatation. Effective therapeutic drugs for AAA patients have not been discovered.
View Article and Find Full Text PDFArticle Synopsis
- * Researchers conducted a time-based semi-quantitative analysis to identify changes in the aortic wall that contribute to AAA, categorizing factors into five specific groups based on their timing of action.
- * Key findings showed that certain proteins and cells related to hypoxia and inflammation are activated early on, indicating that hypoperfusion affects smooth muscle cells in the aorta, helping to unravel the complex processes leading to AAA formation.