Publications by authors named "RenJie Chen"

Heatwaves are commonly simplified as binary variables in epidemiological studies, limiting the understanding of heatwave-mortality associations. Here we conduct a multi-country study across 28 East Asian cities that employed the Cumulative Excess Heatwave Index (CEHWI), which represents excess heat accumulation during heatwaves, to explore the potentially nonlinear associations of daytime-only, nighttime-only, and day-night compound heatwaves with mortality from 1981 to 2010. Populations exhibited high adaptability to daytime-only and nighttime-only heatwaves, with non-accidental mortality risks increasing only at higher CEHWI levels (75th-90th percentiles).

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Lithium-ion batteries (LIBs) have become advanced energy storage technologies; however, specific capacity remains limited by the active materials in cathodes. Here, we report Li-LiNO batteries (LNBs) where LiNO in electrolyte serves as both active materials and ion conductor at room temperature. LNBs operate on a highly reversible redox between NO and NO, which results in an impressive areal capacity of 19 mAh cm at a plateau voltage of 1.

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Background: Despite the fact that 1-year graft and recipient survival rates are above 90% in most transplant centers, improving long-term graft survival remains an important challenge. Immunosuppressant nonadherence has been recognized as one of the important risk factors for long-term graft failure. Understanding the modifiable correlates and risk factors for medication non-adherence is essential to develop interventions to improve adherence and thus long-term transplantation outcomes.

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Fine particulate matter has been linked with acute coronary syndrome. Nevertheless, the key constituents remain unclear. Here, we conduct a nationwide case-crossover study in China during 2015-2021 to quantify the associations between fine particulate matter constituents (organic matter, black carbon, nitrate, sulfate, and ammonium) and acute coronary syndrome, and to identify the critical contributors.

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The response to climate change and air pollution control demonstrates strong synergy across scientific mechanisms, targets, strategies, and governance systems. This report, based on a monitoring indicator system for coordinated governance of air pollution and climate change, employs an interdisciplinary approach combining natural and social sciences. It establishes 20 indicators across five key areas: air pollution and climate change, governance systems and practices, structural transformation and technologies, atmospheric components and emission reduction pathways, and health impacts and co-benefits.

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The COVID-19 pandemic has underscored the importance of indoor environmental management in transportation hubs, which are critical for pathogen transmission due to high foot traffic. However, research has primarily focused on subways, with limited studies on train stations. In this study, samples were collected at the Shanghai Hongqiao Railway Station in winter, spring, and summer.

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Background: Air pollution is a potential risk factor for kidney disease; however, the impact on kidney failure exacerbation is underexplored. This study assessed the short-term effects of air pollution on hospitalization for kidney failure exacerbation.

Methods: This nationwide, time-stratified, case-crossover study included 45,249 hospitalized patients with kidney failure from 153 hospitals in 20 Chinese provinces between 2013 and 2020.

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Background: Epidemiological studies have demonstrated a causal relationship between ambient ozone (O 3 ) and mortality from chronic obstructive pulmonary disease (COPD), which is the only outcome considered in the Global Burden of Disease Study 2021 for O 3 . This study aims to evaluate the temporal trend and spatial distribution of the COPD burden attributable to O 3 across China from 1990 to 2021.

Methods: The ambient O 3 concentrations in China were estimated.

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The thermal safety issues of currently available Ni-rich cathode-based power supplies brought in the development of all-solid-state batteries, yet the cascade reactions in Ni-rich materials and the chemo-mechanical degradation between the cathode and solid electrolyte diminished the cycle life. Here, by introducing a new heteroatom chemical competing diffusion strategy, we successfully stabilize the Ni-rich cathode and the contact face with an solid electrolyte. Combining extensive explorations in theoretical calculation and multiscale in/ex situ characterization, we elucidate the atomic-level chemical competing diffusion upon the topological lithiation of layered materials.

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Importance: Particulate matter exposure has been linked to impaired respiratory health in children, but the respiratory benefits of air purification have not been fully elucidated.

Objectives: To assess the respiratory health outcomes among children exposed to multisetting air purification vs sham purification.

Design, Setting, And Participants: This cluster randomized, double-blind, crossover trial was conducted among healthy school-aged children (10-12 years) in China from April to December 2021.

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Background: There is limited evidence on the risks of second primary malignancies (SPMs) among patients with differentiated thyroid cancer (DTC), particularly in relation to racial disparities. We aim to examine racial and ethnic disparities in the risk and temporal patterns of SPMs among DTC survivors in the U.S.

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Floods are becoming more frequent and severe in the context of climate change, with major impacts on human health. However, their effect on infant mortality remains unknown, particularly in low- and middle-income countries. We conducted a sibling-matched case-control study using individual-level data from Demographic and Health Surveys in Africa during 1990-2020.

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Background: Ambient pollution and non-optimal temperature are major risk factors for respiratory health. However, the relationships between short-term exposure to these factors and bronchiectasis mortality remain unknown.

Methods: A nationwide, time-stratified case-crossover study across Mainland China was conducted from 2013 to 2019.

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To investigate the association of long-term exposure to air pollution with incident arrhythmia from various causes, this prospective cohort study included 442,386 participants from the UK Biobank cohort. Residential annual average exposures at baseline were evaluated, including fine particles (PM), coarse particles (PM), nitrogen dioxide (NO), and nitrogen oxides (NO). We further constructed a composite air pollution score (APS) to evaluate the concomitant exposure to these four pollutants.

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High-voltage Ni-rich layered cathode materials are undoubtedly a powerful driving force for high-energy density lithium batteries. However, residual lithium impurities on the surface of Ni-rich materials can cause more severe side reactions under high-voltage, leading to rapid decay. There is still no reliable mechanistic explanation for this phenomenon.

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The heightened vulnerability of individuals with HIV to environmental stressors is well-recognized, yet the role of air pollution in exacerbating HIV-related mortality remains underexplored. In this nationwide, individual-level case-crossover study conducted from 2013 to 2019, we investigated the association between short-term exposure to criteria air pollutants and HIV-related mortality. Our analysis of 38,510 HIV-related deaths revealed significant associations between exposure to PM, PM, NO, and CO and increased mortality risk.

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Limited evidence was available on ambient air pollution and pediatric atopic dermatitis (AD). The study aimed to evaluate the associations between short-term exposure to air pollutants and outpatient visits for pediatric AD. From 2016-2018, we collected data on six criteria air pollutants (PM, PM, NO, SO, CO and O) and daily outpatient visits for pediatric AD in 66 hospitals, covering all districts in Shanghai, China.

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Article Synopsis
  • Non-optimum ambient temperatures, particularly low temperatures, may significantly increase the risk of myocardial infarction with non-obstructive coronary arteries (MINOCA) compared to those with obstructive coronary artery disease (MI-CAD).
  • A study analyzed data from over 1 million patients between 2015 and 2021, finding that low temperatures posed a higher risk for MINOCA, especially in older individuals, females, and those living in southern regions of China.
  • Results indicated that while the effects of low temperature were substantial, there was no notable difference in the impacts of high temperature on either group of patients.
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Lithium (Li) metal batteries face challenges, such as dendrite growth and electrolyte interface instability. Artificial interface layers alleviate these issues. Here, cellulose nanocrystal (CNC) nanomembranes, with excellent mechanical properties and high specific surface areas, combine with polyvinylidene-hexafluoropropylene (PVDF-HFP) porous membranes to form an artificial solid electrolyte interphase (SEI) layer.

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Accurate exposure assessment is important for conducting PM-related epidemiological studies, which have been limited thus far. In this study, we aimed to develop an ensemble machine learning method to estimate PM concentrations in mainland China during 2013-2020. The study was conducted in two stages.

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Article Synopsis
  • The high overpotential in Li-O batteries (LOBs) is mainly due to slow charge transfer at reaction interfaces, but using a typical LiBr redox mediator can help reduce this overpotential.
  • LiBr RMs face issues like shuttling and corroding the lithium anode, which leads to energy loss and less efficient battery performance.
  • By introducing LiMoO into the LiBr electrolyte, the study enhances the formation of a robust solid electrolyte interphase (SEI) on the lithium anode, resulting in improved cycling stability and energy efficiency for LOBs.
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Article Synopsis
  • The rise of wearable electronics and soft robotics has led to increased research into flexible batteries, which are adaptable for various shapes and sizes in devices like smart systems and sensors.
  • Unlike traditional lithium-ion batteries, flexible batteries consist of materials that can bend and stretch, requiring innovative designs for their components like electrodes and current collectors.
  • The review categorizes flexible batteries into different structures and types, discusses their configurations, and addresses both advancements and ongoing challenges, providing insights for future applications.
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Background: Exposure to ambient ozone has been associated with extrapulmonary health, but the underlying mechanisms remain to be understood. LncRNAs are involved in the regulation of gene expression, but their regulatory mechanisms in ozone-related health effects are scarcely explored.

Objective: To investigate genome-wide lncRNA changes after short-term ozone exposure and their regulatory roles in ozone exposure and gene expression.

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Background: To assess the long-term impact of residential air pollution and green space exposure on cause-specific mortality in individuals with type 2 diabetes mellitus (T2DM).

Methods: This study includes 174,063 participants newly diagnosed with T2DM from a prospective cohort in Shanghai, China, enrolled between 2011 and 2013. Residential annual levels of air pollutants, including fine (PM) and coarse (PM) particulate matter, nitrogen dioxide (NO), along with the normalized difference vegetation index (NDVI), were derived from satellite-based exposure models.

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