Publications by authors named "Ren-Yue Wei"
Introduction: To date, there have been no panoramic studies of the serum metabolome in feline mammary carcinoma. As the first such study, metabolomics techniques were used to analyse the serum of cats with these tumours. Three important metabolic pathways of screened differential metabolites closely related to feline mammary carcinomas were analysed to lay a theoretical basis for further study of the pathogenesis of these carcinomas.
View Article and Find Full Text PDFBackground: Feline mammary carcinoma is the third most common cancer that affects female cats.
Objectives: The purpose of this study was to screen differential serum proteins in feline and clarify the relationship between them and the occurrence of feline mammary carcinoma.
Methods: Chinese pastoral cats were used as experimental animals.
Article Synopsis
- Differentiated cells can be reprogrammed by certain transcription factors, and this study identifies the neural repressor REST as crucial for successful reprogramming in porcine oocytes through nuclear transfer (NT).
- REST levels decrease significantly after oocyte activation, but some of it remains associated with the donor nuclei during the reprogramming process.
- Inhibiting REST function hinders NT embryo development, though it doesn't affect other embryo types; however, this impairment can be reversed by blocking the TGFβ signaling pathway with a specific inhibitor, highlighting REST's important role in NT-mediated reprogramming.