Publications by authors named "Ren-Ye Que"
L. (POL) has a long history of medicinal use worldwide, and numerous clinical and experimental studies demonstrated the therapeutic effects of POL and its active ingredients in the treatment of Ulcerative colitis (UC). In this review, we summarized the underlying mechanisms and roles of POL in UC treatment based on experimental and clinical studies.
View Article and Find Full Text PDFBackground: Both N6-methyladenosine (m6A) methylation and autophagy are considered relevant to the pathogenesis of ulcerative colitis (UC). However, a systematic exploration of the role of the com-bination of m6A methylation and autophagy in UC remains to be performed.
Aim: To elucidate the autophagy-related genes of m6A with a diagnostic value for UC.
Background: Colorectal cancer (CRC) is the third most common cancer worldwide, with the fourth highest mortality among all cancers. Reportedly, in addition to adenomas, serrated polyps, which account for 15%-30% of CRCs, can also develop into CRCs through the serrated pathway. Sessile serrated adenomas/polyps (SSAs/Ps), a type of serrated polyps, are easily misdiagnosed during endoscopy.
View Article and Find Full Text PDFArticle Synopsis
- Ulcerative colitis (UC) is a complex condition influenced by genetic and environmental factors that disrupt immune responses, and researchers are using single-cell RNA sequencing (scRNA-seq) to better understand its biological underpinnings.
- The study aims to identify clinical phenotypes and biomarkers in UC patients to predict their responses to specific therapies, enhancing diagnosis and treatment strategies.
- By analyzing a large dataset of immune cells through various gene analysis methods, researchers found three core genes—RhoB, cathepsin D, and zyxin—that are strongly linked to immune responses and may improve understanding and management of UC.