Background: The association of positive margin and local recurrence after nephron-sparing surgery (NSS) remains a notably controversial issue. The aim of the present study was to investigate the relationship between classification of positive surgical margins (PSMs) and tumor recurrence based pathological findings.
Methods: Clinical, pathological, and follow-up data of 600 small renal cancer patients who underwent NSS between November 2007 and November 2017 at four hospitals in China were analyzed retrospectively.
Recently, dedicator of cytokinesis 2 (DOCK2) has been reportedly exhibited high mutation prevalence in the Asian colorectal cancer (CRC) cohort. However, the expression pattern of DOCK2 and its clinical significance in CRC were still unknown. To characterize the role of DOCK2, a tissue microarray (TMA) containing 481 archived paraffin-embedded CRC specimens was performed by immunohistochemistry.
View Article and Find Full Text PDFInt J Clin Exp Pathol
July 2018
Angiofibroma of soft tissue (AFST) is a recently-reported, rare, fibrovascular soft tissue neoplasm that commonly develops in the lower extremities of middle-aged women. Here, we report three cases located in the right temporal lobe of a woman, the left popliteal fossa of a female, and the right lower limb of a male patient, respectively, the former of which is first reported in the light of a literature review owing to its anatomical location. Histological and immunohistochemical features were consistent with the diagnosis of AFST.
View Article and Find Full Text PDFBackground: This study is to explore the pathological features of transplanted tumor established by CD133 positive TJ905 glioblastoma stem-like cells.
Methods: CD133 positive TJ905 glioma cells were separated by immunomagnetic beads to isolate glioma stem-like cells. TJ905 cells and stem-like cells were inoculated subcutaneously into the mice to establish model of transplanted tumor, respectively.
Zhonghua Bing Li Xue Za Zhi
October 2013
Objective: To investigate the clinicopathological characteristics of sporadic renal hemangioblastoma.
Methods: Two cases of sporadic renal hemangioblastoma were studied by histological and immunohistochemical staining, along with review of the literature.
Results: Both cases were presented with a renal mass during annual physical examination with an age of 40 and 45 years, respectively.
Rom J Morphol Embryol
June 2014
Introduction: Perivascular epithelioid cell tumor (PEComa) has been rarely reported in the liver.
Patient, Methods And Results: We present a liver PEComa case diagnosed by magnetic resonance imaging (MRI) findings. The patient was incidentally found to have an abnormal mass in the liver.
Zhonghua Bing Li Xue Za Zhi
April 2011
Zhonghua Bing Li Xue Za Zhi
March 2007