Function Study of Different Negative Charge Pullulan Nanoparticles for Sentinel Lymph Node Angiography.

Background: Many dyes or radioactive markers used for sentinel lymph node (SLN) have the shortcomings of false positive and radiation injury. Indocyanine green (ICG) seems to have a lower false positive rate and tissue damage, without a clear field of vision during the operation.

Methods: For the shortcomings, we successfully synthesized three anionic pullulan materials, changed the degree of hydrophobic for size controlling (< 50nm) to prepare CHP nanoparticles (NPs) and changed the succinyl degree to prepare CHPC NPs with different negative surface potential.

Subspecies Classification and Comparative Genomic Analysis of HL1 and M1 for Potential Niche-Specific Genes and Pathways.

(1) Background: Strains HL1 and M1, isolated from kefir grains, have been tentatively identified, based on their partial 16S rRNA gene sequences, as . The two strains demonstrated different health benefits. Therefore, not only the genetic factors exerting diverse functionalities in different strains, but also the potential niche-specific genes and pathways among the strains, should be identified.

Co-Culture Strategy of HL1 for Developing Functional Fermented Milk.

Our previous studies indicated that HL1, isolated from kefir grain, has strong antioxidant activities and anti-aging effects. However, this strain is difficult to use in isolation when manufacturing fermented products due to poor viability in milk. Thus, the purpose of this study was to apply a co-culture strategy to develop a novel probiotic fermented milk rich in HL1.

Selective fluorescence sensor based on ion-imprinted polymer-modified quantum dots for trace detection of Cr(VI) in aqueous solution.

A new fluorescence sensor (QDs-IIP), based on ion-imprinted polymers (IIP) as recognition element and Mn-doped ZnS quantum dots (QDs) as fluorophore, was synthesized for the selective and sensitive determination of hexavalent chromium (Cr(VI)) ions. The QD was first coated by SiO layer, and then modified with Cr(VI)-imprinted polymer. Several parameters affecting fluorescence intensity such as tetraethylorthosilicate (TEOS) volume, ZnS:Mn@SiO amount, and radiation time were investigated and optimized.