[Analysis of the Urban Water Eco-environment Protection Strategy in the Beijing-Tianjin-Hebei Region from "Three Waters" Overall Planning].

Clarifying the direction and strategy of water eco-environment protection in the Beijing-Tianjin-Hebei region is of great significance for realizing the water eco-environment protection and high-quality, coordinated development of the Beijing-Tianjin-Hebei area, as well as the goal of building a beautiful China by 2035. From the perspective of "Three Waters" overall planning, based on the urban scale of the Beijing-Tianjin-Hebei region, this study constructed six dimensions of water resources, water environment, water ecology (Three Waters), socio-economic development level, pollutant emissions, and environmental governance efforts. The water eco-environment protection strategy analysis system provided a logical framework for quantifying the current status of the water eco-environment.

Protective effect of Phaeoporus obliquus polysaccharide against acute liver injury induced by carbon tetrachloride and alcohol in mice.

Studied the optimum extraction process of polysaccharide from Phaeoporus obliquus and the effect of Phaeoporus obliquus polysaccharide on carbon tetrachloride (CCl)- or alcohol-induced acute liver injury in mice. The main factor in influencing the extraction rate of Phaeoporus obliquus polysaccharide were extraction power and time, which was a kind of pyran glucose by infrared spectroscopy. CCl and alcohol were employed respectively to establish CCl4 and alcohol-induced acute liver injury mouse models.

Rhein lysinate decreases inflammation and adipose infiltration in KK/HlJ diabetic mice with non-alcoholic fatty liver disease.

The objective of this study was to investigate the protective effects of rhein lysinate (RHL) on the liver. Mice were divided into four groups: C57BL/J control, the KK/HlJ diabetic model, and 25 and 50 mg/kg/day RHL-treated KK/HlJ groups. The KK/HlJ diabetic mouse model was made by injecting STZ and feeding mice diabetic food.

Vasoactive intestinal peptide induces vascular endothelial growth factor production in human HaCaT keratinocytes via MAPK pathway.

Psoriasis is a chronic skin disease characterized by abnormal keratinocyte proliferation and differentiation, inflammation, and angiogenesis. Although dysfunction of the immune system is known to be an important factor in the pathogenesis of psoriasis, there is also strong evidence that psychological stresses are involved. Neuropeptides are thought to be main mediators of neurogenic inflammation, presumably involved in the pathogenesis of psoriasis.

Association between serum soluble membrane type matrix metalloproteinase-1 (MT1-MMP) levels and bone mineral density, and biochemical markers in postmenopausal women.

Background: Recently, membrane type matrix metalloproteinase-1 (MT1-MMP) was found to participate in bone metabolism. We investigated the relationship between serum MT1-MMP and bone mineral density (BMD) as well as bone metabolic markers in 206 Chinese postmenopausal women aged 43-80 years.

Methods: Western analysis and ELISA were performed to detect serum soluble MT1-MMP levels.

[Effect of nutrient support on severe infant pneumonia].

Objective: To explore the effect of nutrient support on severe infant pneumonia.

Methods: Prospective study was conducted on the outcome of 567 inpatients suffering from severe pneumonia in 13 hospitals randomly selected in Hunan. Twelve factors were surveyed and data analyzed by multiple logistic regression.

Apelin and its receptor are expressed in human osteoblasts.

Objectives: Apelin is a recently discovered peptide that is the endogenous ligand for the orphan G-protein-coupled receptor APJ. Adipocytes can express and secrete apelin. The aim of this study was to characterize apelin and APJ expression in human osteoblasts and to investigate the effects of apelin on osteoblasts.