Publications by authors named "Ren Wei Wang"
Article Synopsis
- The primary electrophysiological abnormalities in Parkinson's disease are increased beta oscillations and excessive burst discharges in the subthalamic nucleus (STN), directly linked to locomotor issues.
- In a rat model, while the loss of dopaminergic neurons and STN burst discharges develop quickly after a lesion, beta oscillation changes take longer, reflecting differing timescales in behavioral deficits.
- STN burst discharges appear to be a direct result of dopaminergic depletion, while beta oscillations may represent secondary changes that indicate subtler cortical dysfunctions in Parkinson's disease.
Article Synopsis
- * In parkinsonian rats, there's a notable decrease in α rhythms and coherence between the motor cortex (MC) and subthalamic nucleus (STN), leading to abnormal movement patterns.
- * DBS therapy can improve movement by restoring normal oscillations between MC and STN, but careful electrode management is vital since overstimulation can lead to undesirable behaviors like restlessness.
Objective: Lennox-Gastaut syndrome (LGS) is an epileptic encephalopathy frequently associated with multiple types of seizures. The classical Na channel inhibitors are in general ineffective against the seizures in LGS. Rufinamide is a new Na channel inhibitor, but approved for the treatment of LGS.
View Article and Find Full Text PDFBackground: Trunk function in stroke patients with hemiplegia is associated with respiration and core stability and is also found to be associated with balance and postural control and activities of daily living. LiuZiJue Qigong (LQG) is a traditional Chinese method of fitness based on breath pronunciation. The purpose of this study is to compare the clinical efficacy of LQG and traditional core stability training in the treatment of stroke patients with abnormal trunk posture.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the impact of personalized aerobic exercise and a low carbohydrate diet on reducing liver fat content in individuals with pre-diabetes and non-alcoholic fatty liver disease (NAFLD).
- It involves a 6-month randomized trial with 200 participants who are divided into four groups, each receiving different combinations of exercise and diet interventions, while also comparing with healthy and non-NAFLD pre-diabetes reference groups.
- The primary outcomes focus on changes in hepatic fat content, gut microbiota, and metabolic markers, aiming to highlight the effectiveness of lifestyle modifications in managing these health conditions.