Synthesis and cytotoxic activities of organometallic Ru(II) diamine complexes.

A series of mono and bimetallic ruthenium(II) arene complexes bearing diamine (Ru) were prepared and fully characterized by H, C, F, and P NMR spectroscopy and elemental analysis. The crystal structure of the bimetallic complex (Ru) was determined by X-ray crystallography. Monometallic analogues (Ru) were synthesized to investigate the contributions of ruthenium and the other organic groups (aren, ethylenediamine, butyl) to the activity.

Effects of adipose and bone marrow-derived mesenchymal stem cells on vaginal atrophy in a rat menopause model.

Background & Objectives: Vaginal atrophy is characterized by thinning of vaginal epithelial layers and decreased local blood flow. We aimed to evaluate the regenerative effects of Adipose derived mesenchymal stem cells (ADMSC) and Bone marrow derived mesenchymal stem cells (BMDSC) on vaginal atrophy in rat menopause model.

Materials And Methods: Rats were randomly divided into 4 (four) groups: sham, control, ADMSC, BMDSC.