Publications by authors named "Remy Legrand"
Article Synopsis
- Behavioral weight loss programs are effective in reducing health risks and improving outcomes, but long-term data on their impact is limited, prompting this large study with over 10,000 participants to evaluate a specific nutritional and psycho-behavioral rehabilitation program (RNPC).
- The study is conducted across 92 centers in France and will analyze various data points, including health conditions, medication use, and sleep-related measures over a span of two years, with follow-ups lasting up to five years.
- Ethical approval has been obtained, and study findings will be published in peer-reviewed journals and presented at conferences, potentially shaping future research on the RNPC's effectiveness.
Obstructive sleep apnea (OSA) is one of the most frequent chronic diseases, and comorbid obesity occurs in more than 60% of cases. Variations in body weight influence both OSA severity and OSA-related symptoms. We prospectively assessed the impact of a weight-loss program using the Berlin score to reflect OSA risk, and we also used the Epworth Sleepiness Scale (ESS) to assess daytime sleepiness.
View Article and Find Full Text PDFAlthough high-protein diets appear to be the most efficient way to lose weight, concerns may arise about their innocuity on renal function. The objective of this study is to assess the impact of a weight loss program on renal function. A multicentric cohort-based study was performed using the RNPC© French national weight loss program.
View Article and Find Full Text PDFBackground: Dietary intervention is a cornerstone of weight loss therapies. In obesity, a dysbiotic gut microbiota (GM) is characterized by high levels of Bacteroides lineages and low diversity. We examined the GM composition changes, including the Bacteroides 2 enterotype (Bact2), in a real-world weight loss study in subjects following a high-protein hypocaloric diet with or without a live microorganisms (LMP) supplement.
View Article and Find Full Text PDFThe aim of this study was to assess the impact of the nationwide total lockdown (LD) in France on weight loss and body composition modifications in subjects participating in a weight loss program and to evaluate the impact of remote consultations on participants' adherence to the weight loss program. The CO-RNPC study was a prospective multicentre cohort study including participants undergoing a two to six months program. The rate of weight loss in kg/week was computed before (15 days), during (99 days) and after LD (15 days).
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