[ACUTE RESPIRATORY DISTRESS SYNDROME CAUSED BY BETA-LACTAM ANTIBIOTICS].

We report a case of iatrogenic lesion of the lungs in a 61 year old patient following simultaneous subtotal resection and plastic surgery of esophagus using a gastric stem with the removed cardial portion along with subtotal mediastinal lympho-dissection for the treatment of 2 x 1 cm T2NoMO tumour in the middle third of esophagus. The patient's medical history contained no evidence of previous pulmonary pathology, preoperative chest X-ray study revealed neither focal nor infiltrative changes in the lungs. On day 5 after extensive surgical intervention with the use of a parenteral beta-lactam antibiotic, the patient developed acute respiratory distress the symptoms of which increased wavelike during the next 4.

COMETARY SCIENCE. The nonmagnetic nucleus of comet 67P/Churyumov-Gerasimenko.

Knowledge of the magnetization of planetary bodies constrains their origin and evolution, as well as the conditions in the solar nebular at that time. On the basis of magnetic field measurements during the descent and subsequent multiple touchdown of the Rosetta lander Philae on the comet 67P/Churyumov-Gerasimenko (67P), we show that no global magnetic field was detected within the limitations of analysis. The Rosetta Magnetometer and Plasma Monitor (ROMAP) suite of sensors measured an upper magnetic field magnitude of less than 2 nanotesla at the cometary surface at multiple locations, with the upper specific magnetic moment being <3.

[Efficacy of Venarus in treatment of patients with post-thrombotic disease of lower limbs].

The authors studied efficacy of Venarus in comprehensive treatment of patients presenting with post-thrombotic disease. An open multicenter retrospective study included a total of 110 patients subdivided into two groups. Group One (Study Group) consisted of 51 patients with post-thrombotic syndrome, undergoing comprehensive medical treatment with the use of phlebotonic agent Venarus.

[The role of nanotechnology in creating novel antitumor agents].

Nanobiotechnology, defined as an arm of a nano-system is a rapidly developing area of medicine. Nanomaterials ranging from 1 to 1000 nm in size offer unique advantages of interaction with biological systems on the molecular level. Nanobiotechnologies can be used in definition, diagnosis and treatment of cancer thus leading to the new development of a new discipline--nanooncology.

[First experience with minilaparotomy for Leriche syndrome].

The authors present the first experience with reconstruction of the terminal part of the infrarenal aorta from minilaparotomy. There were 11 aortofemoral bifurcation shunts in patients with Leriche syndrome. In two cases conversion (general calcification of the aorta, visceral obesity) was necessary.

Vibrational spectra and structure of isopropylbenzene.

Infrared spectra (4,000-400 cm(-1)) and Raman spectra (1,700-40 cm(-1)) of the liquid and two crystalline solids of isopropylbenzene (cumene) and isopropylbenzene-d(12) have been recorded. The spectra indicate that in the liquid and crystalline solids isopropylbenzene exists in planar conformation only (CH bond is in the plane of the benzene ring). An assignment of the observed band wave numbers both isopropylbenzene and isopropylbenzene-d(12) is discussed by comparison with normal mode wave numbers and IR intensities calculated from ab initio 6-31G (d) force fields.

[Esophagoplasty in patients with the "waning" stomach or without the stomach].

An experience with 48 intrathoracic esophagoplasties in patients with "waning" stomach or its absence is generalized. The results obtained show that scarry-ulcerous damages of the pyloroduodenal and cardioesophageal portions, local surgical procedures, gastrostomy included, are not considered as deterrent factors for using the stomach as the plasty material for esophagoplasty. For the resected stomach or its absence the small intestine should be preferred in the formation of the anastomosis within the limits of the thoracic cavity and large intestine--when putting anastomosis on the neck.

The vibrational spectra and conformations of ethylbenzene.

Infrared spectra (4000-250 cm-1) of the liquid, amorphous, crystalline solids and solutions in liquid krypton and Raman spectra (2500-20 cm-1) of the liquid as well as the amorphous and crystalline solids of ethylbenzene and its deuterated analogue-ethylbenzene-d(10) have been recorded. The spectra indicate that in the liquid and amorphous solids a small amount of a second conformer is present, whereas only one conformer remains in the crystalline phases. Assignments of the observed band wave numbers are discussed by comparison with normal mode wave numbers and IR and RS intensities calculated from ab initio 6-31G force fields and optimised geometries for both conformers for two species.

Internal rotation in 1,2-di-(p-XC6H4)ethanes (X=H, Br, NO2): infrared spectra and compensation effect.

Infrared absorption spectra and internal rotation of 1,2-di-(p-XC(6)H(4))ethanes (X=H, Br, NO(2)) in crystalline phase, liquid and solutions at various temperatures have been investigated. Band fitting was applied to conformationally sensitive regions of the spectra, and assignment of the peaks to trans and gauche conformations was performed. Enthalpy and entropy differences of the conformers (deltaH(0) and deltaS(0)) were found to be solvent-dependent, and it is interpreted in terms of previously discovered compensation effect.

Infrared E-type band profiles of acetonitrile in condensed media: orientational diffusion and free rotation.

Infrared spectra of liquid acetonitrile (CH3CN) and its solutions in CCl4, CS2, chloroform, dichloromethane, benzene-d6, acetone-d6 and dimethyl sulfoxide-d6 have been studied. E-type bands under investigation (v5 = 3009, v6 = 1448 and v7 = 1041 cm(-1)) were reproduced by the sum of two Cauchy-Gauss components, the narrower (n) and the broader (b) ones. The different temperature behaviour of the components has been found: the integrated intensities of the narrower components, In, decrease with the temperature, while the intensities of the broader ones, Ib, increase.

[Dependence of the intensity of 2,4,6-trinitrotoluene-induced mutagenesis on the physiological state of tester strains of Salmonella typhimurium].

The dependence of the mutagenic potential of 2,4,6-trinitrotoluene (TNT) on the growth phase of the Salmonella typhimurium tester strains TA100 and TA98 is shown. The mutagenic potential proved to be maximal for log-phase cultures, being higher with strain TA100 than TA98. The amount of TNT absorbed by bacteria in the first minutes of contact varied, depending on culture age, and was the largest at the beginning of the exponential growth phase.

[The course on medical physics].

The definition of medical physics is given, the main directions of the course are described, and some practical examples are provided. Analysis is made of the status of the problem concerned with teaching medical physics.

[An experimental basis for cochlear prosthesis].

The experimental studies on cochlear prosthesis, performed at the II Moscow's medical Institute since 1981, are described. Electrophysiological and morphological results from the trial of an original electronic prosthesis, which transduces sound into electric oscillations, are presented. Data are given on morphological studies, referring to the influence of cochlear implants on the basal curve of the cochlea, to the internal structures of the cochlea and of the acoustic zone in the cortex of the large hemispheres.

[Free radicals formed during UV-irradiation of biological membrane lipids].

Formation of free radicals under UV-irradiation of egg phosphatidyl choline, and synthetic phosphatidyl cholines and their analogs, as well as of their model compounds was studied. When saturated fat lipids are UV-irradiated radicals--CH2CH2 are accumulated at the expense of the breakage of--CH2CH2--COOH-bond. Radicals CH3--OCH2, HCO are formed in aminoalcohols due to the breakage of --OCH2--CH2N+(CH3)3- and--CH2--N+(CH3)3-bonds.

[Free radicals formed during UV-irradiation of unsaturated fatty acids containing peroxidation products].

On the irradiation of oxidized linolic acid an assymetric ESR signal with g-factor 2.0039 and the linewidth 30--33 Oe has been registered. The signal could be the result of photolysis of hydroperoxides.

[Chromolymphography in the oncological surgical clinic].

A new Soviet preparation for colour lymphography--chromolymphotrast--is presented in this paper. Radiopaque lymphography with the use of chromolymphotrast was carried out upon more than 50 patients with carcinoma of the uterine cervix and of the body of the womb. Besides, there is information concerning a successful use of the chromolymphotrast in cases of cancer of the vulva, mammary gland and rectum.

[Study of the effect of corticosterone on erythrocyte membranes by the spin label method].

Influence of corticosterone on the hare's erythrocyte ghosts is studied by the spin-label method. There exists a correlation between the maximal variation region in the rotational diffusion "frequency" of the spin-labels, covalently linked with the membrane protein, and the hormones concentration range within which the effect of corticosterone on the functions of the erythrocyte membranes manifests itself to the greatest degree (permeability to ions, hemolytic effects, etc).

[Antitumor action of new 2,4-diethyleneimino-6-amino-sym.-triazina derivatives].

In experiments of mice and rats with transplantable tumors (sarcoma 37, sarcoma 45, ascites Ehrlich tumor, etc) the authors studied the antitumor activity of a number of new water-soluble derivatives of 2,4-diethylenimino-6-amino-sym.-triazine differing only in the substituting radical associated with sym.-triazine cycle.