Publications by authors named "Remi Chieze"
Article Synopsis
- Primary hyperparathyroidism (PHPT) is often linked with high calcium levels, while normocalcemic primary hyperparathyroidism (NHPT) can be easily misdiagnosed.
- A study analyzed patients with hypercalciuric kidney stones to compare characteristics and prevalence of NHPT versus hypercalcemic hyperparathyroidism (HPHPT), revealing that NHPT accounts for 40% of PHPT cases.
- The results found no significant differences in parathyroid characteristics or stone composition between NHPT and HPHPT, but indicated that NHPT patients showed a stronger response to calcium loading, highlighting the importance of dynamic testing for accurate diagnosis.
The urine concentration impairment responsible for hyposthenuria in sickle cell nephropathy is currently thought to be a consequence of renal medulla lesions, which lead to nephrogenic diabetes insipidus. The objective of the present study was to investigate the mechanism of hyposthenuria in patients with sickle cell anemia. We performed an observational study of patients with homozygous SS sickle cell anemia and data available on the fasting plasma antidiuretic hormone (ADH) concentration.
View Article and Find Full Text PDFPrimary hyperparathyroidism (pHPT) has been reported to have a higher prevalence in sickle cell disease (SCD) patients, including a high rate of recurrence following surgery. However, most patients are asymptomatic at the time of diagnosis, with surprisingly infrequent hypercalciuria, raising the issue of renal calcium handling in SCD patients. We conducted a retrospective study including (1) 64 hypercalcemic pHPT non-SCD patients; (2) 177 SCD patients, divided into two groups of 12 hypercalcemic pHPT and 165 non-pHPT; (3) eight patients with a diagnosis of familial hypocalciuric hypercalcemia (FHH).
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