Publications by authors named "Remeniak O"
Article Synopsis
- Excessive reactive oxygen species and oxidative stress play a major role in cholangitis, suggesting that antioxidants like C fullerene could be effective therapeutics.
- In experiments with rats, C fullerene significantly improved liver and pancreas conditions during both acute and chronic cholangitis by normalizing biochemical markers, reducing inflammation, and lowering fibrotic changes.
- C fullerene showed a stronger therapeutic effect than the standard drug prednisolone and inhibited certain cell expressions linked to liver damage.
Background: Cisplatin (Cis-Pt) is a widely used anticancer drug but its therapeutic efficiency is limited by hemato-, cardio-, hepato-, nephro- and neurotoxicity. Complexation of Cis-Pt with C fullerene nanoparticle will allow to enhance the antitumor activity of the drug and to reduce its side toxic effects.
Aim: To estimate the antitumor effects of С60-Cis-Pt nanocomplex in Lewis lung carcinoma (LLC) and analyze hematological toxicity in tumor-bearing mice.
Unlabelled: It is proposed to use the novel paradigm of treating cancer with hyperthermic therapy using multi-walled carbon nanotubes (MWCNT) stimulated with near infrared (NIR) irradiation.
Aim: To establish the capacity of MWCNT stimulated with NIR irradiation to destroy Erlich ascitic carcinoma (EAC) cells.
Materials And Methods: EAC cells suspension was irradiated with NIR heating lamp with a wavelength of 0.