Publications by authors named "Remedios Guadalupe Gomez-Mauricio"
A preliminary approach to the repair of myocardial infarction using adipose tissue-derived stem cells encapsulated in magnetic resonance-labelled alginate microspheres in a porcine model.
Remedios Guadalupe Gomez-Mauricio Argia Acarregui Francisco Miguel Sánchez-Margallo Verónica Crisóstomo Ignacio Gallo
Eur J Pharm Biopharm
May 2013
Article Synopsis
- Adipose tissue-derived stem cells (ASCs) can be beneficial for treating heart damage due to their self-renewal and growth capabilities, but their effectiveness is hindered by poor retention at injury sites.
- Researchers created semipermeable microcapsules (magnetocapsules) to protect and track ASCs using MRI, helping to maintain the cells' environment and improve their retention in heart tissue.
- Results show that these magnetocapsules enhanced the viability of ASCs in culture and improved their in vivo retention compared to non-encapsulated cells, although there were no significant changes in heart function metrics during the study period.