Study of outcome after targeted intervention for peptic ulcer resistant to acid suppression therapy.

Objective: Different factors might affect outcome in ulcers resistant to antisecretory therapy. The aim of the study was to define the odds of resistant ulcers being associated with NSAID use, and/or Helicobacter pylori (H. pylori) infection, or neither.

[Acute azathioprine-induced pancreatitis in a female patient with Crohn's disease].

A case of acute pancreatitis induced by azathioprine presented in a 22-year-old patient with Crohn's disease is reported. The patient erroneously took the drug once again repeating the appearance of acute pancreatitis, earlier and with greater severity.

[Primary intestinal T lymphoma].

Primary gastrointestinal lymphoma comprises a group of distinctive clinicopathological entities. They may be of B or T-cell type. Intestinal T-cell lymphomas are much less common and include the entity: lymphomas T enteropathy-associated T-cell lymphoma, the most common, and T-cell lymphoma without features of enteropathy.

Risk factors associated with refractory peptic ulcers.

Background & Aims: The risk factors associated with refractory peptic ulcers are still undefined. The purpose of this study was to identify these factors in a multivariate context.

Methods: Clinical and endoscopic findings as well as Helicobacter pylori status, gastric secretion analysis, serum gastrin levels, nonsteroidal anti-inflammatory drug (NSAID) use, and objective testing of aspirin use by platelet cyclooxygenase activity were studied in 60 consecutive refractory patients with peptic ulcer and 54 matched nonrefractory controls.