Indian J Crit Care Med
August 2023
Solomon R. Predicting Pediatric ICU Outcomes: Yet Another SOFA (Study) on the PODIUM? Indian J Crit Care Med 2023;27(8):526-528.
View Article and Find Full Text PDFIndian J Crit Care Med
August 2022
Solomon R. Pediatric Acute Respiratory Distress Syndrome in India: Time for Collaborative Study? Indian J Crit Care Med 2022;26(8):896-897.
View Article and Find Full Text PDFObjective: This study was done to analyze the profile of confirmed pediatric TB patients seen in an intensive care setting.
Methods: Data of all children admitted in our PICU with bacteriologically proven tuberculosis (smear, culture, poly-merase chain reaction, genotypic testing or Pyrosequencing) between January, 2007 and December, 2019 were retrieved. Drug resistance was classified as per World Health Organization definitions.
Background: Multisystem inflammatory syndrome (MIS) associated with severe acute respiratory syndrome coronavirus (SARS-CoV-2) (MIS-C) in children is being increasingly reported across the world.
Materials And Methods: Children fulfilling the World Health Organization criteria of MIS-C needing pediatric intensive care unit between April 15 and July 26, 2020 were studied.
Results: There were 21 patients with median age of 7 years [interquartile range (IQR) 1.
The objectives were to determine if tumor necrosis factor (TNF)-α, leukotriene (LT)B4 and 8-isoprostane (IP) were present in the exhaled breath condensate (EBC) and total lung lavage (TLL) of mechanically ventilated rats, 4 and 24 h after administration of Staphylococcal entertoxin (SEB) and to find out if these mediators in the EBC correlate with the concentration in the TLL. Rats were assigned to control (n = 8); 4 h (n = 8) or 24 h (n = 8) groups after SEB. The rats were mechanically ventilated and EBC and TLL were collected for TNF-α, LTB4 and 8-IP.
View Article and Find Full Text PDFPartial atrioventricular septal defect is usually followed by an uncomplicated postoperative course. We present an infant with unexplained persistent respiratory failure following partial a trioventricular septal defect repair. Extensive evaluation including bronchoalveolar lavage subsequently led to the diagnosis of disseminated cytomegalovirus.
View Article and Find Full Text PDFExhaled breath condensate (EBC) may contain mediators of acute lung injury. The objectives were to determine if EBC could be collected in a mechanically ventilated rat, to measure tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in the EBC after staphylococcal enterotoxin B administration (SEB) and to find out if the concentrations of TNF-α and IL-6 correlated with those in lung lavage. Four hours after SEB instillation, rats were placed on mechanical ventilation and EBC was collected over 90 minutes.
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