Photoprotective sulfated mannogalactan from heterotrophic Bacillus velezensis blocks UV-A mediated matrix metalloproteinase expression and nuclear DNA damage in human dermal fibroblast.

Prolonged exposure of human dermal fibroblasts (HDF) to ultraviolet (UV) radiation triggers the production of reactive oxygen species by upregulating the expression of matrix metalloproteinases (MMPs), causing type-I collagen degradation and photoaging. A sulfated (1 → 3)/(1 → 4) mannogalactan exopolysaccharide (BVP-2) characterized as [→3)-α-Galp-{(1 → 4)-α-6-O-SO-Manp}-(1 → 3)-α-6-O-SO-Galp-(1→] was isolated from seaweed-associated heterotrophic bacterium Bacillus velezensis MTCC13097. Whole genome analysis of B.

Occurrence of Deep-sea shrimp, Hadropenaeus lucasii (Spence Bate, 1881) from the southwest coast of India.

The present study provides an integrative report combining morphological and molecular analysis of the deep sea shrimp species Hadropenaeus lucasii (Spence Bate, 1881) from the southwest coast of India. The present specimen was obtained from the depths of 200-300m from the commercial bottom trawlers operated off Sakthikulangara fishing harbour off Kollam, Kerala. A phylogenetic analysis was used to explore the relationships of the genus.

Seaweed-associated heterotrophic bacteria: are they future novel sources of antimicrobial agents against drug-resistant pathogens?

Emergence of multidrug-resistant microorganisms and requirements for novel antimicrobial compounds necessitate exploring newer habitats to develop potential bioactive leads. Culture-contingent analysis of heterotrophic bacterial flora from the seaweeds led to the isolation of bioactive strains possessing potential antibacterial properties against wide-ranging clinical pathogens viz., methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus faecalis (VREfs).

Antibiotic-active heterotrophic Firmicutes sheltered in seaweeds: can they add new dimensions to future antimicrobial agents?

Appearance of drug-resistant microorganisms prompted researchers to unravel new environments for development of novel antimicrobial agents. Culture-supported analysis of heterotrophic bacteria associated with seaweeds yielded 152 strains, in that larger share of the isolates was embodied by Bacillus atrophaeus SHB2097 (54%), B. velezensis SHB2098 (24%), B.

Bacillibactin class of siderophore antibiotics from a marine symbiotic Bacillus as promising antibacterial agents.

Preliminary antibacterial metabolite production screening unveiled that B. amyloliquefaciens MTCC 12,713 associated with the intertidal red alga Kappaphycus alverezii exhibited potential inhibitory effects against drug-resistant pathogens methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecalis, Pseudomonas aeruginosa, and Klebsiella pneumoniae. Four homologous siderophore types of bacillibactins were isolated from a heterotrophic marine bacterium through bioactivity-guided purification.

Novel amylomacins from seaweed-associated Bacillus amyloliquefaciens as prospective antimicrobial leads attenuating resistant bacteria.

The rise in antibiotic-resistant bacterial strains prompting nosocomial infections drives the search for new bioactive substances of promising antibacterial properties. The surfaces of seaweeds are rich in heterotrophic bacteria with prospective antimicrobial substances. This study aimed to isolate antibacterial leads from a seaweed-associated bacterium.

A Leap Forward Towards Unraveling Newer Anti-infective Agents from an Unconventional Source: a Draft Genome Sequence Illuminating the Future Promise of Marine Heterotrophic Bacillus sp. Against Drug-Resistant Pathogens.

During the previous decade, genome-built researches on marine heterotrophic microorganisms displayed the chemical heterogeneity of natural product resources coupled with the efficacies of harnessing the genetic divergence in various strains. Herein, we describe the whole genome data of heterotrophic Bacillus amyloliquefaciens MB6 (MTCC 12,716), isolated from a marine macroalga Hypnea valentiae, a 4,107,511-bp circular chromosome comprising 186 contigs, with 4154 protein-coding DNA sequences and a coding ratio of 86%. Simultaneously, bioactivity-guided purification of the bacterial extract resulted in six polyketide classes of compounds with promising antibacterial activity.

Marine macroalga-associated heterotrophic Bacillus velezensis: a novel antimicrobial agent with siderophore mode of action against drug-resistant nosocomial pathogens.

Increased prevalence of microbial resistance and development of drug-resistant pathogens have triggered an urge among researchers to discover potential antimicrobial compounds, particularly from the marine habitat. The present study highlights the cultivable diversity and bioactivities of heterotrophic bacteria associated with marine macroalgae of southeast Indian coastal region. Culture-dependent isolation method resulted in 40 isolates, in which greater part of the isolates represented Gammaproteobacteria (62%) followed by that comprised of the phylum Firmicutes.

DNA barcoding of deep-sea shrimp Sicyonia parajaponica Crosnier, 2003 (Crustacea: Decapoda: Sicyoniidae) from southwest coast of India.

The present work reports detailed taxonomic information on deep-sea shrimp Sicyonia parajaponica from southwest Indian waters. The samples were caught in bottom trawls conducted between the depths of 200 and 230 m from Sakthikulangara fishing harbour off Kollam, Kerala along the Arabian Sea during November 2019. DNA barcoding and a phylogenetic analysis was used to explore the relationship of the genus Sicyonia based on mitochondrial cytochrome c oxidase subunit 1 (COI: MN816389, MN816390) with the present specimen and sequences retrieved from NCBI GenBank.

Misidentification and notes on Plesionika semilaevis, Spence Bate, 1888 (Crustacean: Decapoda: Caridea) from the southern coast of India.

The commercial deep-sea caridean shrimp Plesionika martia (Milne-Edwards 1883) has long been recorded from India and constitutes an important species of deep-sea shrimp catches in the southern coast of India. However, the present study revealed that all the previous records of "Plesionika martia" is actually a misidentification of the closely related species P. semilaevis, which was recently obtained from Indian waters.

Pharmacological properties of some mangrove sediment-associated bacillus isolates.

Mangrove sediment-associated bacteria are of significantly important in the field of medicine and pharmaceuticals as new promising sources of biologically active pharmacophores due to the extreme conditions, such as high salt concentration and soil anoxia. The sediment bacteria associated with Acanthus ilicifolius and Avicennia officinalis collected from the Mangalavanam mangrove ecosystem of the Kerala State of India were evaluated using various in vitro models for the assessment of their pharmacological properties. The bacteria exhibiting significant antioxidant and antimicrobial activities were isolated, identified, and characterized by the integrated microbiological, biochemical, and 16S rRNA sequencing.

Moving away from traditional antibiotic treatment: can macrocyclic lactones from marine macroalga-associated heterotroph be the alternatives?

Intertidal red algae Hypnea valentiae associated Bacillus amyloliquefaciens MTCC 12716 revealed potential inhibitory effects on the growth of drug-resistant pathogens. In the genome of B. amyloliquefaciens MTCC 12716, biosynthetic gene clusters encoding antibacterial metabolites were predicted, which might be expressed and contributed to the broad-spectrum anti-infective activity.

A new record of deep-sea shrimp Glyphocrangon investigatoris Wood-Mason amp; Alcock, 1891 (Decapoda: Glyphocrangonidae) from the southeastern Arabian Sea.

Here, we report the new record of deep-sea caridean shrimp Glyphocrangon investigatoris Wood-Mason Alcock, 1891 from the Arabian Sea along the Indian coast. The three individual specimens were collected from Sakthikulangara fish landing center (fishing off Kollam 8°56'60.78"N/76°32'34.

A new species of the deep-sea squat lobster genus Eumunida Smith, 1883 (Decapoda: Anomura: Eumunididae) from the Arabian Sea off southwestern India.

A new species of the squat lobster genus Eumunida Smith, 1883 (Chirostyloidea: Eumunididae), E. multispina, is described and illustrated primarily on the basis of two male specimens from the Arabian Sea off the Kerala State, southwestern India, at depths of 250-400 m. One specimen from Lakshadweep, previously identified with E.

Integrative taxonomy of commercially important deep water penaeoid shrimps from India.

The deep water penaeoid shrimp is an important commercial crustacean resource along the Indian coast. The molecular and morphological information of this group from the Indian coast is scarcely known. In this study, we investigated the identification and phylogenetic relationships of the deep water penaeoid shrimps using three mitochondrial (cytochrome oxidase subunit I (COI), cytochrome b, 16S rRNA) genes, which were compared with 54 morphological characters and further used to evaluate character evolution.

First record of deep-sea caridean shrimp Acanthephyra fimbriata Alcock Anderson, 1894 (Crustacea: Decapoda: Acanthephyridae) from southwest coast of India.

The present work reports the new occurrence of deep-sea shrimp Acanthephyra fimbriata Alcock Anderson, 1894 from southwestern Indian waters. The samples were caught in bottom trawls conducted between the depths of 200 and 350 m from two fish landing centers off Kerala along Arabian Sea from the southwest coast of India during 2015. Additionally, a phylogenetic analysis was used to explore the relationships of the genus Acanthephyra based on two genes: mitochondrial cytochrome c oxidase subunit 1 (COI) and 16S DNA (16S) with the present specimen and sequences retrieved from NCBI GenBank.

Record of the deep sea shrimp Pasiphaea alcocki (Wood-Mason Alcock, 1891) (Crustacea: Decapoda: Pasiphaeidae) from the southwestern coast of India.

The present study provides a report on the rare occurrence of the deep sea caridean shrimp Pasiphaea alcocki (Wood-Mason Alcock, 1891) from the southwest coast of India after three decades. Earlier this species was recorded from Indian waters at a depth range between 335 and 1732 m while the present specimens were obtained in the depth range of 200-300m from the commercial bottom trawlers operated off Sakthikulangara fishing harbour (8°56'60.78"N /76°32'34.

Two new records of deep sea shrimp under the genus Parapontocaris (Crustacea: Decapoda: Crangonidae) from the southwestern coast of India.

This paper reports the occurrence of two species of the crangonid genus Parapontocaris Alcock, 1901 in waters off  Kerala from the southwestern coast of India, viz. P. levigata (Chace 1984) and P.

New records of Pontocaris affinis affinis (Alcock, 1901) and Pontocaris propensalata Spence Bate, 1888 (Crustacea: Decapoda: Crangonidae) from Quilon bank of Southeastern Arabian Sea.

This paper reports on two crangonid shrimps, Pontocaris affinis affinis and Pontocaris propensalata from Southeastern Arabian Sea. Continuous surveys in the Quilon bank yielded two new records of Pontocaris, which were found on the continental slope at 250-300 m depth. A 4.

On Plesionika persica (Kemp, 1925) and P. reflexa Chace, 1985 (Crustacea: Decapoda: Pandalidae) from India.

The availability of Indian specimens of Plesionika persica (Kemp, 1925) and P. reflexa Chace, 1985 provided more information on the taxonomy around these two species. Moreover, it is the first record of P.

New records of Crosnier, 1994 and Ramadan, 1938 (Crustacea: Decapoda: Penaeoidea) from the southwest coast of India.

The genus Solenocera Lucas, 1849 consist of 43 species, most with commercial importance and occurring in offshore, deeper waters (Pérez Farfante & Kensley 1997; De Grave & Fransen 2011). Twelve species in the genus Solenocera were reported from India, with a few contributing to the regular fishery (S. crassicornis, S.

O-heterocyclic derivatives with antibacterial properties from marine bacterium Bacillus subtilis associated with seaweed, Sargassum myriocystum.

The brown seaweed, Sargassum myriocystum associated with heterotrophic bacterium, Bacillus subtilis MTCC 10407 (JF834075) exhibited broad-spectra of potent antibacterial activities against pathogenic bacteria Aeromonas hydrophila, Vibrio vulnificus, and Vibrio parahaemolyticus. B. subtilis MTCC 10407 was found to be positive for polyketide synthetase (pks) gene, and therefore, was considered to characterize secondary metabolites bearing polyketide backbone.