Nanosecond Laser Cataract Surgery in LOCS III Grade 4 and 5: A Case Series.

Purpose: A major obstacle to the widespread implementation of nanosecond laser cataract removal has been its limited efficacy in cases when the cataract is harder than Lens Opacities Classification System III (LOCS III ) grade 3. The latest technological modifications seem to have overcome this obstacle.

Design: A case series.

Ablation of lens epithelial cells with a laser photolysis system: histopathology, ultrastructure, and immunochemistry.

Purpose: To evaluate efficacy of a neodymium:YAG (Nd:YAG) laser photolysis system in removing lens epithelial cells (LECs) and characterize the effect of the laser on laminin and fibronectin involved in LEC adhesion and migration.

Methods: Cadaver eyes were evaluated using the Miyake technique. The lenses were removed with phacoemulsification.

Prevention of lens capsule opacification with ARC neodymium:YAG laser photolysis after phacoemulsification.

We describe a technique that uses a neodymium:YAG (Nd:YAG) laser photolysis system to prevent lens capsule opacification. The photolysis instrument consists of a 1064 nm Nd:YAG laser transmitted along a fiber-optic cable into a handpiece containing an angulated titanium plate that the laser beam strikes, creating plasma and a shockwave that exits the handpiece through an aperture. Under direct visualization, the shockwave is aimed at the inner surface of the anterior capsule, where it removes LECs and proteoglycan attachment molecules; the shockwave probably extends to the capsule fornix, destroying germinal epithelial cells.