Surgical treatment of chronic osteomyelitis in children admitted from developing countries.

Background: The surgical management of chronic osteomyelitis in children is still challenging in developing countries. This study analysed the extent of the disease and the therapeutic regime.

Subjects And Methods: This was a retrospective study in two primary health care hospitals from January 2009 to December 2013, 27 children (20 males and 7 females, mean age 7 years) admitted from developing countries who were treated for chronic osteomyelitis.

Prospective collection of error data in orthopaedic and trauma surgery procedures.

Purpose: The frequency, type and consequences of errors in orthopaedic and trauma surgery procedures should be analysed.

Methods: In a level II trauma centre, errors and intraoperative complications were prospectively recorded concerning type, severity, preventability and consequences. The error-related time delay was also noted.

Multicentric giant cell tumor of bone: synchronous and metachronous presentation.

A 27-year-old man treated 2.5 years ago for synchronous multicentric giant cell tumor of bone located at the right proximal humerus and the right 5th finger presented now with complaints of pain in his right hip and wrist of two-month duration. Radiology and magnetic resonance revealed multicentric giant cell tumor lesions of the right proximal femur, the left ileum, the right distal radius, and the left distal tibia.

Treatment for displaced proximal humerus fractures: comparison of interlocking plate fixation versus minimal invasive techniques.

Background And Purpose: The functional results and the complications following interlocking plate fixation of displaced proximal humerus fractures should be evaluated and compared with those following minimal invasive fixation techniques.

Patients And Methods: Fifty patients (30 women, 20 men, mean age 62.7 (18-91) years) were treated for a displaced proximal humerus fracture using an interlocking plate fixation (PHILOS®) between 2003 and 2004.

Absence of telomerase activity in malignant bone tumors and soft-tissue sarcomas.

Purpose: Telomerase activity appears to play a crucial role in the development of many tumors. More than 80% of all malignant human tumors show an increased telomerase activity. However, conflicting results have been reported about telomerase activity in sarcomas.

Preoperative embolization in spinal and pelvic metastases.

The role of preoperative embolization should be evaluated for the surgical treatment of spinal and pelvic metastases. Selective embolization was performed in 32 patients (19 men, 13 women; mean age 63.4 years) before surgery by anterior resection of spinal metastases (n = 21) or pelvic metastases (n = 11).

Genetic instability in primary leiomyosarcoma of bone.

Primary leiomyosarcoma (LMS) of bone is an exceedingly rare entity on which to date no molecular data have been reported. In a series of 6 tumors (5 grade IIB, 1 grade IIA), we assessed the prevailing genetic stability by microsatellite analysis at 7 loci. The IIB tumors demonstrated a rate of genomic loss as high as 90%, accompanied by an intratumoral heterogeneity in 30% of conspicuous markers.