Activity optimization method in SPECT: a comparison with ROC analysis.

A discriminant method for optimizing activity in nuclear medicine studies is validated by comparison with ROC (received operating characteristic)-curves. The method is tested in 21 single photon emission computerized tomography (SPECT), performed with a cardiac phantom. Three different lesions (L(1), L(2) and L(3)) were placed in the myocardium-wall by pairs for each SPECT.

Administered activity optimization in 99mTc-MAG3 renography for adults.

Objective: The objective of this work was to determine the minimum administered activity of (99m)Tc-mercaptoacetyltriglycine (MAG3) needed both to estimate effective renal plasma flow (ERPF) with adequate precision and to obtain good image quality.

Methods: Three groups of 10 patients each were injected with 45, 71, or 132 MBq of MAG3. Renograms and perfusion and clearance images were obtained.