Oropouche virus - another antecedent event for Guillain-Barré syndrome?

In May 2024, the Pan American Health Organization issued alerts of increased numbers of cases of Oropouche fever in non-Amazonian regions in Latin America. Following this, an association between Oropouche fever and Guillain-Barré syndrome was reported in three patients in Santiago de Cuba, Cuba. Neurological manifestations have rarely been described in relation to Oropouche virus infection.

Sandhoff disease in the elderly: a case study.

Sandhoff disease is an infrequent, genetically caused disorder with a recessive autosomal inheritance pattern. It belongs to the gangliosidosis GM2 group and is produced by mutations in gen leading to reduction in enzymatic activity of enzymes β-hexosaminidase A and B. Adult-onset GM2 gangliosidosis is rare.