Effects of timolol maleate eye drops on experimentally dilated cardiomyopathy and healthy rabbits.

Background: Dilated cardiomyopathy (DCM) is the most frequently diagnosed cardiomyopathy in rabbits. Timolol maleate (nonselective beta-blockers), which reduces the heart rate (HR) and blood pressure, has been used for glaucoma. However, this effect has not been assessed in a rabbit DCM model.

Surgical ventricular restoration for rabbit dilated cardiomyopathy model: Preliminary study.

Dilated cardiomyopathy (DCM) is a common cardiovascular disease in dogs. It is primarily treated with beta-blockers. The aim of this preliminary study was to evaluate the efficacy of surgical ventricular restoration on daunorubicin-induced DCM in rabbits.