Whole body hyperthermia supplemented with urotropin in the treatment of malignant tumors.

Aim: To evaluate the effect of urotropin on the tolerance of an extreme whole body hyperthermia (WBH) regime (44.5-45.0 degrees C for 60 min) in rats, and then its application to pediatric patients with advanced cancer during WBH sessions (42.

Whole body hyperthermia in adjuvant therapy of children with renal cell carcinoma.

Whole body hyperthermia (WBH) in combination with chemotherapy has been proven to be effective in some patients with advanced malignancies. However, only limited experience exists regarding the application of WBH with chemotherapy in children. We present the results of applying WBH and chemotherapy in five children with advanced renal cell carcinoma (RCC).

Enhancement of antitumor response to sarcoma 45 in rats by combination of whole-body hyperthermia and interleukin-2.

Aim: To evaluate the summarized effect of hyperthermia and interleukin-2 (IL-2) administration on antitumor defense in tumor-bearing rats.

Methods: Nonbred rats after subcutaneous inoculation of sarcoma 45 cells were treated with whole-body hyperthermia (WBH, +42.5 degrees C, 60 min) and interleukin-2 (IL-2, 10,000 U/kg of body weight).