Publications by authors named "Reika Hayashi"
Article Synopsis
- The study focuses on establishing effective short-term remission criteria for lupus nephritis (LN) that can help predict long-term outcomes at 5 years using kidney biopsies and clinical data.
- It evaluated 23 patients 2 years after induction therapy, defining two key long-term goals based on disease activity and proteinuria levels.
- The findings indicate that specific short-term goals, particularly "A at 2 years," reliably forecast long-term success and demonstrate a strong correlation between clinical and histological remission.
Background: Despite the high efficacy of mycophenolate mofetil (MMF)/tacrolimus-based multitarget treatment, risks of infections are a matter of concern. In the present study, we clarified the potential of multitarget therapy using mizoribine opposed to MMF.
Methods: A total of 36 patients with biopsy-proven lupus nephritis were treated with mizoribine, tacrolimus, and glucocorticoids and then retrospectively evaluated.