Publications by authors named "Reijnierse M"

: The objective of our study was to evaluate the association and frequency of subcutaneous lymphedema in patients with gout primarily affecting the feet. : In 79 patients with acute gout, ultrasound (US) and dual-energy computed tomography (DECT) were performed to assess the presence of subcutaneous edema and extra- and intra-articular gouty deposits. In addition, the diagnostic utility of two post-processing DECT protocols were evaluated, comprising different minimum attenuation thresholds of 150 HU (DECT 150 protocol) and 120 HU (DECT 120 protocol), with the same maximum attenuation threshold (500 HU) and constant kilovoltage setting of tubes A and B at 80 and 140 kVp.

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Objective: MRI of the hands is valuable for risk-stratification in patients with arthralgia at-risk for developing rheumatoid arthritis (RA). Contrast-enhanced MRI is considered standard for assessment of RA, but has practical disadvantages. It also shows inflammation-like features in the general population, especially at older age, which should be considered in image interpretation.

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Objectives: This study aims to establish expert consensus recommendations for clinical information on imaging requests in suspected/known axial spondyloarthritis (axSpA), focusing on enhancing diagnostic clarity and patient care through guidelines.

Materials And Methods: A specialised task force was formed, comprising 7 radiologists, 11 rheumatologists from the Assessment of Spondyloarthritis International Society (ASAS) and a patient representative. Using the Delphi method, two rounds of surveys were conducted among ASAS members.

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Background: A range of sacroiliac joint (SIJ) MRI protocols are used in clinical practice but not all were specifically designed for diagnostic ascertainment. This can be confusing and no standard diagnostic SIJ MRI protocol is currently accepted worldwide.

Objective: To develop a standardised MRI image acquisition protocol (IAP) for diagnostic ascertainment of sacroiliitis.

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Objectives: Apply a modified Delphi-based approach and produce a practical, radiology-specific set of definitions for interpretation and standardization of the multiple MRI findings in axial spondyloarthritis (ax-SpA), specifically to aid the general radiologist with a musculoskeletal interest, working with gold standard basic MRI protocols.

Materials And Methods: We report the results of a modified Delphi-based consensus of 35 experts from 13 countries in the Arthritis Subcommittee of the European Society of Musculoskeletal Radiology (ESSR). Seventeen definitions were created (i.

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Whereas previous projects attempted to standardize imaging in patients with axial spondyloarthritis (axSpA), few studies have been published about the need for specific details regarding the image acquisition and lesions that may be less familiar to general radiologists. This work reports consensus recommendations developed by the Assessment of SpondyloArthritis International Society (ASAS) that aim to standardize the imaging reports in patients suspected of having or with known axSpA. A task force consisting of radiologists and rheumatologists from ASAS and one patient representative formulated two surveys that were completed by ASAS members.

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Objectives: To assess the association of posterior element (PE) and facet joint (FJ) inflammation with subsequent new FJ ankylosis (FJA) on MRI, in patients with radiographic axial spondyloarthritis (r-axSpA).

Methods: Patients from the Sensitive Imaging in Ankylosing Spondylitis cohort, inclusion criteria r-axSpA and ≥1 radiographic spinal syndesmophyte, were studied. MRI of the full spinal was performed at baseline, 1 and 2 years.

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Article Synopsis
  • Artificial intelligence, particularly deep learning, has influenced everyday life and is now being explored in fields like rheumatology for diagnostics and patient monitoring.* -
  • Deep learning excels at processing images, outperforming traditional imaging techniques, but its effectiveness may not translate to simpler numerical data analysis.* -
  • Rheumatologists and radiologists must understand deep learning's techniques and limitations to incorporate it effectively into their practices, ensuring they leverage its benefits while avoiding potential pitfalls.*
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Background: Rotator cuff calcific tendinitis (RCCT) is a commonly occurring disease, with a prevalence of up to 42.5% in patients with shoulder pain. RCCT is characterized by hydroxyapatite deposits in the tendons of the rotator cuff and is considered a self-limiting disease that can be treated nonoperatively.

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Article Synopsis
  • Scientists noticed a new type of inflammation in the hand tendons of people with rheumatoid arthritis and those at risk, which might happen before arthritis symptoms show up.
  • They ran an MRI study on adults with joint pain and healthy people to see how often this tendon inflammation occurs and how it relates to other joint problems.
  • The study included 667 patients and helped researchers understand if tendon inflammation could be an early sign of rheumatoid arthritis.
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Background: The Computed Tomography Syndesmophyte Score (CTSS) was developed as a reliable and sensitive tool to assess syndesmophytes in low-dose CT images of the entire spine in patients with axial spondyloarthritis (axSpA). The original paper provided sparce examples of the CTSS grades.

Objectives: Provide an atlas tailored to assist readers in understanding and employing the CTSS method.

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Article Synopsis
  • * Ultrasound offers dynamic assessments and can guide interventions, while MRI is useful for diagnosing specific injuries and conditions like metatarsal stress fractures and Lisfranc injuries.
  • * The review also covers imaging of common masses and joint disorders in the foot, emphasizing the importance of knowing the anatomy for accurate diagnosis.
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Article Synopsis
  • - The article discusses the effectiveness of conventional radiography (CR) for assessing sacroiliac joints in adults and juveniles suspected of having axial spondyloarthritis (axSpA), comparing it to MRI and CT.
  • - The subcommittees highlight MRI's superior ability to detect early sacroiliitis, emphasizing its importance for accurate diagnosis, particularly in children where it poses no radiation risk.
  • - While CR is suitable for identifying structural changes in late-stage axSpA or established cases, additional imaging methods may be necessary for adult differential diagnoses related to the pelvis.
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  • This study aimed to investigate how much vertebral corner fat accumulation contributes to the formation of syndesmophytes in patients with radiographic axial spondyloarthritis (r-axSpA).
  • Researchers analyzed data from two cohorts, assessing inflammation and fat deposition at multiple time points and using imaging techniques to evaluate the development of syndesmophytes.
  • The results indicated that while inflammation increased the likelihood of syndesmophyte formation, only a small fraction of that effect was explained by fat deposition at the vertebral corners.
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Objective: Inflammation around the tendons of the hand interosseous muscles (interosseous tendon inflammation [ITI]) was recently identified on magnetic resonance imaging (MRI) in a set of patients with rheumatoid arthritis (RA) and arthralgia. We conducted a large MRI study to assess the prevalence of ITI at diagnosis of RA and of other arthritides, as well as its relationship with clinical signs.

Methods: A total of 1,205 patients presenting with various types of early arthritis between 2010 and 2020 underwent contrast-enhanced hand MRI as part of the prospective Leiden Early Arthritis Cohort.

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Objectives: To assess construct validity of the CT Syndesmophyte Score (CTSS) for the measurement of structural spinal damage in patients with radiographic axial spondyloarthritis.

Methods: Low-dose CT and conventional radiography (CR) were performed at baseline and 2 years. CT was assessed with CTSS by two readers and CR with modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS) by three readers.

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Magnetic resonance imaging (MRI) of the axial skeleton, spine, and sacroiliac (SI) joints is critical for the early detection and follow-up of inflammatory rheumatologic disorders such as axial spondyloarthritis, rheumatoid arthritis, and SAPHO/CRMO (synovitis, acne, pustulosis, hyperostosis, and osteitis/chronic recurrent multifocal osteomyelitis). To offer a valuable report to the referring physician, disease-specific knowledge is essential. Certain MRI parameters can help the radiologist provide an early diagnosis and lead to effective treatment.

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Article Synopsis
  • The study looked at how inflammation affects bone density in people's spines who have a condition called radiographic axial spondyloarthritis (r-axSpA).
  • Researchers found that inflammation was linked to lower bone density, but lower bone density didn't actually lead to new bone growth over 2 years.
  • The conclusion is that it’s more important to focus on reducing inflammation to prevent bone issues than just trying to fix the bone density itself.
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Objectives: To describe low dose Computed Tomography (ldCT) Hounsfield Units (HU) two-year change-from-baseline values (expressing trabecular bone density changes) and analyse their inter-reader reliability per vertebra in radiographic axial spondyloarthritis (r-axSpA).

Methods: We used 49 patients with r-axSpA from the multicentre two-year Sensitive Imaging in Ankylosing Spondylitis (SIAS) study. LdCT HU were independently measured by two trained readers at baseline and two years.

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Objective: MRI of small joints plays an important role in the early detection and early treatment of rheumatoid arthritis. Despite its sensitivity to demonstrate inflammation, clinical use is hampered by accessibility, long scan time, intravenous contrast, and consequent high costs. To improve the feasibility of MRI implementation in clinical practice, we introduce a modified Dixon sequence, which does not require contrast and reduces total acquisition time to 6 min.

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Objectives: To investigate the associations between MRI detected vertebral corner inflammation (VCI) and vertebral corner fat deposition (VCFD) on whole spine low-dose CT scan (ldCT) detected syndesmophyte formation and growth.

Methods: Patients from the Sensitive Imaging in Ankylosing Spondylitis cohort underwent MRI (baseline, 1 year and 2 years) and ldCT (baseline and 2 years). MR images were scored by three readers for VCI and VCFD, MRI patterns were defined by presence of VCI and/or VCFD over 2 years.

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Article Synopsis
  • - MRI reveals that inflammation around the extensor tendons of metacarpophalangeal (MCP) joints is common in rheumatoid arthritis (RA) and signals a higher risk of developing RA in patients with joint pain.
  • - The inflammation, referred to as 'peritendinitis,' may actually involve a synovial lining, as previous studies haven't confirmed the presence of a tenosynovial sheath at these tendons.
  • - An anatomical study of three embalmed human hands showed signs of synovial tissue, suggesting that early MRI contrast enhancement may indicate tenosynovitis, marking inflammation as an initial sign of RA.
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Objective: Studying vertebral bone loss in radiographic axial spondyloarthritis (r-axSpA) has been challenging due to ectopic bone formation. We cross-sectionally analysed low-dose CT (ldCT) trabecular bone density Hounsfield units (HU) measurements and calculated inter-reader reliability at the vertebral level in patients with r-axSpA.

Methods: LdCT scans of 50 patients with r-axSpA from the sensitive imaging in ankylosing spondylitis study, a multicentre 2-year prospective cohort were included.

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Crystal arthropathies are a group of joint disorders due to deposition of crystals in and around joints that lead to joint destruction and soft tissue masses. Clinical presentation is variable and diagnosis might be challenging. In this article the pathophysiology is addressed, the preferred deposition of crystal arthropathies and imaging findings.

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