Further validation of the Parent-Reported ADHD Symptom Infrequency Scale (PRASIS) in parents of children with oppositional defiant disorder and anxiety.

This study aimed to validate a novel parent-report measure of ADHD symptom inflation, the Parent-Reported ADHD Symptom Infrequency Scale (PRASIS), in a clinical sample. The PRASIS is composed of an Infrequency subscale and an ADHD subscale. Online participants were assigned to one of three groups: mothers of children with diagnosed ADHD ( = 110), mothers of children with diagnosed ODD and/or anxiety ( = 116), and mothers of children without ADHD, ODD, or anxiety.

Validation of an adult ADHD measure of feigning in a sample including individuals with depression and anxiety symptoms.

Few studies of measures or techniques designed to detect feigning of Attention-Deficit/Hyperactivity Disorder (ADHD) have included groups reporting symptoms of depression and anxiety. Based on the high rate of comorbidity between ADHD and mood disorders, inclusion of such groups is important to mimic clinical referral patterns. The current study evaluated the validity of the ADHD Symptom Infrequency Scale (ASIS), a measure designed to detect malingered symptoms of ADHD, in a four-known groups design that included a group consisting of subjects with symptoms of anxiety and depression.

The parent-reported ADHD symptom infrequency scale (PRASIS): a parent report measure of ADHD symptom exaggeration.

The present article outlines the development of the parent-reported ADHD symptom infrequency scale (PRASIS), a novel stand-alone questionnaire designed to discriminate between parents exaggerating ratings of ADHD symptoms of their child from parents more accurately reporting symptoms. The PRASIS includes an Infrequency scale (INF) to measure infrequently reported symptoms of ADHD and a clinical scale to measure Diagnostic and Statistical Manual of Mental Disorders-5 Edition (DSM-5) defined ADHD symptoms (ADHD Total). An initial list of infrequency and clinical items was revised over the course of three studies, each conducted on a different sample of participants ( = 154,  = 203,  = 167) recruited via CloudResearch and consisting of mothers of children 4-12 years old.

Emotion Dysregulation and Workplace Satisfaction in Direct Care Worker Burnout and Abuse Risk.

Background/objectives: Direct care workers frequently encounter difficult interactions with the patients they serve and experience frustration and burnout. The current study tested a hypothesized model in which predictors of caregiver abuse risk (emotional dysregulation, difficulty managing patient behavior, and workplace satisfaction) were mediated by symptoms of burnout.

Design: The study used an online cross-sectional survey design.

Minnesota Multiphasic Personality Inventory-Adolescent-Restructured Form (MMPI-A-RF) characteristics of ADHD in a Korean psychiatric sample.

Global rates of attention-deficit/hyperactivity disorder (ADHD) have risen. In Korea, ADHD is associated with functional impairments and comorbidity with other psychological disorders. This study examined the correlates of ADHD in a psychiatric sample of Korean adolescents on the Minnesota Multiphasic Personality Inventory-Adolescent-Restructured Form (MMPI-A-RF).

Youth Concussion Management Practices Among Athletic Trainers: A Vignette-Based Survey.

Context: Recovery protocols for treatment of sports concussion have received widespread adoption across the country. While stages of recovery and treatment are relatively clearly defined, there remains variability in implementation of specific recommendations, particularly regarding activities that constitute rest during stages calling for limitations on activity participation. Specific recommendations being employed by practitioners have not been previously assessed.

The ADHD Symptom Infrequency Scale (ASIS): A novel measure designed to detect adult ADHD simulators.

The current project outlines the development of the Attention-Deficit/Hyperactivity Disorder (ADHD) Symptom Infrequency Scale (ASIS), a stand-alone measure designed to identify individuals feigning or exaggerating symptoms to receive a diagnosis of ADHD. Over the course of 3 studies, valid data was collected from 402 participants assigned to control, simulator, ADHD diagnosed, or possible undiagnosed ADHD groups. Group assignment was based on self-reported history of ADHD diagnosis including information about the credentials of diagnosing professional and methods used.

Effects of Bone-Marrow-Derived MSC Transplantation on Functional Recovery in a Rat Model of Spinal Cord Injury: Comparisons of Transplant Locations and Cell Concentrations.

Spinal cord injury (SCI) is a widely disabling condition, constraining those affected by it to wheelchairs and requiring intense daily care and assistance. Cell replacement therapies, targeting regeneration of cells in the injured cord, are currently gaining momentum in the field of SCI research. Previous studies indicate that mesenchymal stem cells (MSCs) can reduce functional deficits through immunomodulation and production of trophic factors in a variety of neurological disorders.

Learning style, judgements of learning, and learning of verbal and visual information.

The concept of learning style is immensely popular despite the lack of evidence showing that learning style influences performance. This study tested the hypothesis that the popularity of learning style is maintained because it is associated with subjective aspects of learning, such as judgements of learning (JOLs). Preference for verbal and visual information was assessed using the revised Verbalizer-Visualizer Questionnaire (VVQ).

Cognitive ability predicts motor learning on a virtual reality game in patients with TBI.

Background: Virtual reality games and simulations have been utilized successfully for motor rehabilitation of individuals with traumatic brain injury (TBI). Little is known, however, how TBI-related cognitive decline affects learning of motor tasks in virtual environments.

Objective: To fill this gap, we examined learning within a virtual reality game involving various reaching motions in 14 patients with TBI and 15 healthy individuals with different cognitive abilities.

Cortisol and self-report measures of anxiety as predictors of neuropsychological performance.

Although increased anxiety and cortisol reactivity can disrupt neural activity and impact cognition, little research has evaluated associations between anxiety, cortisol, and performance on neuropsychological instruments. The current study investigated the relationship between exogenous salivary cortisol activity and self-report state anxiety on measures tapping a variety of cognitive domains. Fifty-eight male participants were randomly assigned to either a control (no stress induction) or an experimental condition simulating testing anxiety.

Genetically engineered mesenchymal stem cells reduce behavioral deficits in the YAC 128 mouse model of Huntington's disease.

The purpose of this study was to evaluate the therapeutic effects of the transplantation of bone-marrow mesenchymal stem cells (MSCs), genetically engineered to over-express brain-derived neurotrophic factor (BDNF) or nerve growth factor (NGF) on motor deficits and neurodegeneration in YAC 128 transgenic mice. MSCs, harvested from mouse femurs, were genetically engineered to over-express BDNF and/or NGF and these cells, or the vehicle solution, were injected into the striata of four-month old YAC 128 transgenic and wild-type mice. Assessments of motor ability on the rotarod and the severity of clasping were made one day prior to transplantation and once monthly, thereafter, to determine the effects of the transplanted cells on motor function.

Development of a novel malingering detection method involving multiple detection strategies.

This study utilized a novel computer-administered measure designed to assess multiple malingering detection strategies, as well as measure genuine impairment in a brain-injured sample. Ninety-four neurologically normal subjects comprised control and simulator groups. Twenty individuals with moderate to severe head injuries comprised a clinical sample.

Personality and performance-based measures in the prediction of alcohol use.

Research has demonstrated a variable relationship between alcohol consumption and self-report personality measures of novelty seeking and harm avoidance. Research has also demonstrated a relationship between performance-based measures of risk taking and substance use. The current study compared the utility of personality measures and performance-based measures in the prediction of alcohol use.

A pilot investigation of the effects of stress on neuropsychological performance in Asian-Indians in the United States.

The present study evaluated the effects of stress and the ethnicity of the examiner on neuropsychological performance in a sample of Asian-Indian males in the United States. Participants were 60 Asian-Indian college students randomly assigned to one of four conditions in a 2 x 2 factorial design. The first factor was level of stress induction and the second was ethnicity of examiners.

The relationship between visual contrast sensitivity and neuropsychological performance in a healthy elderly sample.

Visual acuity and contrast sensitivity are two visual domains affected by normal aging; however, the potential impact of well-documented changes in these abilities on neuropsychological assessment is relatively unstudied. The current study examined the relationship between these abilities and neuropsychological performance in a healthy, community-based elderly sample. Fifty-one individuals (Age: M = 79.

African American women: a life course of care?

Twenty-five years of research on family care to dependent elders has produced a theoretically sophisticated understanding of the process of family caregiving. Although caregiving models initially were developed and tested on predominantly White samples, more recent work has applied these models to African American caregivers. This investigation builds on the comparative perspective by describing elder care in African American families through the eyes of the culture in which it occurs.

Comparison of Predicted-difference, Simple-difference, and Premorbid-estimation methodologies for evaluating IQ and memory score discrepancies.

Discrepancies between WAIS-III and WMS-III scores for a group of 39 males and 48 females with a history of TBI were examined using three methodologies: Predicted-difference, Simple-difference, and Premorbid-estimation methods. Overall, the Predicted-difference method tended to classify the fewest individuals as impaired based on statistical rarity of discrepancies (11-16% classified as impaired), while the regression-based Premorbid method tended to classify the fewest individuals as impaired based on clinical rarity of discrepancies (4-8% classified as impaired). Degree of agreement is reported and was substantial.

The relationship between performance-based visual acuity screening, self-reported visual acuity, and neuropsychological performance.

Despite frequent cautions in the literature concerning the importance of visual acuity in neuropsychological testing, there are few published empirical investigations of what constitutes "sufficient" visual acuity, nor are there published guidelines for performance-based visual screening techniques. The current study attempted to validate the utility of a visual acuity screening technique by examining individuals with varying visual ability on neuropsychological measures. Results revealed declines on neuropsychological measures associated with reduced visual acuity, as well as discrepancies between self-reported and measured visual acuity, with neuropsychological performance being more closely related to a performance-based measure of visual acuity than to self-reported visual acuity.

Challenges facing health professionals caring for HIV-infected drug users.

Although injection drug use accounts for only 5% to 10% of cumulative HIV infections globally, it is a more efficient way of spreading HIV than sexual intercourse. HIV epidemics among injection drug users (IDUs) have a potential for rapid spread of the virus within the IDU community and outward into the general population. Effective interventions addressing this mode of HIV transmission are needed because part of a comprehensive strategy to curb the spread of HIV infection.