Publications by Reid Martin Rubsamen

Publications by authors named "Reid Martin Rubsamen"

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An Approach for a Synthetic CTL Vaccine Design against Zika Flavivirus Using Class I and Class II Epitopes Identified by Computer Modeling.

Edecio Cunha-Neto Daniela S Rosa Paul E Harris Tim Olson Alex Morrow Reid Martin Rubsamen

Front Immunol

June 2017

The threat posed by severe congenital abnormalities related to Zika virus (ZKV) infection during pregnancy has turned development of a ZKV vaccine into an emergency. Recent work suggests that the cytotoxic T lymphocyte (CTL) response to infection is an important defense mechanism in response to ZKV. Here, we develop the rationale and strategy for a new approach to developing cytotoxic T lymphocyte (CTL) vaccines for ZKV flavivirus infection.

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- Reid Martin Rubsamen's recent research primarily focuses on the development of synthetic vaccines targeting the Zika flavivirus, specifically utilizing cytotoxic T lymphocyte (CTL) responses for effective immunity against the virus.
- In his 2017 article, Rubsamen proposes a new vaccine design methodology that incorporates Class I and Class II epitopes, identified through computer modeling, to enhance the CTL response against Zika virus infections.
- This research underscores the urgency of developing a Zika vaccine amidst concerns over severe congenital defects arising from maternal infections, highlighting the potential role of CTL in combating viral threats during pregnancy.

Publications by authors named "Reid Martin Rubsamen"

An Approach for a Synthetic CTL Vaccine Design against Zika Flavivirus Using Class I and Class II Epitopes Identified by Computer Modeling.

Synopsis of recent research by authors named "Reid Martin Rubsamen"