Publications by authors named "Reich S"

Background: Household transmission of respiratory viruses may drive community spread. Few recent studies have examined household respiratory syncytial virus (RSV) transmission in the United States.

Methods: We conducted a prospective community-based cohort study from 1 June 2022 to 31 May 2023.

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The optical excitation of close-by molecules can couple into collective states giving rise to phenomena such as ultrafast radiative decay and superradiance. Particularly intriguing are one-dimensional molecular chains that form inside nanotube templates, where the tubes align molecules into single- and multifile chains. The resulting collective excitations have strong fluorescence and shifted emission/absorption energies compared to the molecular monomer.

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We examined longitudinal direct associations between mothers' and fathers' emotion socialization behaviors (ESB) at 18 and 24 months and toddlers' social competence (SC) at 24 and 30 months in a sample of ethnically diverse families (n = 128) participating in a parenting intervention study. We also investigated interaction effects between mothers' and fathers' ESBs and between each parent's ESBs and child emotionality. We coded parents' ESBs to their toddlers' positive and negative emotions during no-toy play and a clean-up task.

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Background: Respiratory syncytial virus (RSV) is the leading cause of hospitalization among infants in the United States (US). RSV immunization, in the form of a monoclonal antibody (mAb) for infants and vaccines for pregnant people, may reduce infant RSV risk.

Methods: In April and May 2023, we surveyed adults with children in Oregon and Washington about the likelihood to accept infant mAb and maternal RSV vaccine and RSV awareness.

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Objective: In recent decades, CAD/CAM-fabricated lithium disilicate restorations have become popular and have been approved for fixed dental protheses (FDPs) up to the second premolar since 2013. This multicenter follow-up study collected long-term clinical data on three-unit anterior and premolar FDPs made of lithium disilicate to evaluate the material's suitability over >10 years.

Methods: Thirty-two patients received a total of 32 three-unit anterior or premolar monolithic lithium disilicate FDPs.

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This report describes the design, development, and optimization of an electrochemical deoxyfluorination of arenes using a tetrafluoropyridine-derived leaving group. NEt·3HF serves as the fluoride source, and the reactions are conducted using either constant potential or constant current electrolysis in an undivided electrochemical cell. Mechanistic studies support a net oxidative pathway, in which initial single-electron oxidation generates a radical cation intermediate that is trapped by fluoride.

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Genetic diagnosis of rare diseases requires accurate identification and interpretation of genomic variants. Clinical and molecular scientists from 37 expert centers across Europe created the Solve-Rare Diseases Consortium (Solve-RD) resource, encompassing clinical, pedigree and genomic rare-disease data (94.5% exomes, 5.

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Background: Infections with fluconazole-resistant Candida parapsilosis have been increasing in Israeli hospitals with unclear implications for patient outcomes.

Objectives: To determine the frequency, mechanisms, molecular epidemiology, and outcomes of azole-resistant C. parapsilosis bloodstream infections in four hospitals in Israel.

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Article Synopsis
  • Dystonia is a common movement disorder with a complex genetic background, showing significant variability in its clinical presentation and genetics.
  • The study involved exome sequencing of nearly 1,924 patients, mainly from two major registries, focusing on those with genetic prescreening negative results and early age at onset.
  • Researchers discovered 137 likely pathogenic variants in 51 genes among the patients, with many being novel, highlighting the challenges in diagnosing and understanding the disorder's genetic links.
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  • Vibrational Raman scattering involves energy exchange between light and molecular vibrations, notably described in quantum terms where both are quantized.
  • When these vibrations occur within a plasmonic nanocavity, as seen in surface-enhanced Raman scattering (SERS), the setup acts as an optomechanical cavity that enhances light-vibration interactions, leading to potential advancements in vibrational state manipulation and nonlinear optics at the nanoscale.
  • This Perspective aims to bridge the concepts of molecular cavity optomechanics (McOM) and traditional methods, summarizing current progress and challenges while emphasizing parameters crucial for enhancing light-matter interactions in the context of SERS and nanoplasmonics.
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  • Cervical dystonia (CD) is a common neurological condition, with about one-third of patients also experiencing tremors in their head and hands, complicating diagnosis and treatment.
  • Researchers analyzed data from over 3,100 CD patients across various continents using machine learning to identify clinical features predicting the presence and nature of neck tremor.
  • Key findings revealed that increased severity of CD, longer disease duration, and older age were strong predictors of neck tremor, with notable differences in tremor characteristics based on gender and the involvement of other body parts.
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Developmental plasticity enables the production of alternative phenotypes in response to different environmental conditions. While significant advances in understanding the ecological and evolutionary implications of plasticity have been made, understanding its genetic basis has lagged. However, a decade of genetic screens in the model nematode has culminated in 30 genes which affect mouth-form plasticity.

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Article Synopsis
  • A large-scale genome-wide association study (GWAS) was conducted with over 6000 participants to investigate genetic risk factors for isolated dystonia, aiming to improve upon earlier studies that found no significant genetic links.
  • The study included 4303 dystonia patients and 2362 healthy controls, analyzing various factors like age of onset and affected body areas, but ultimately failed to identify any common genetic variants associated with dystonia.
  • The findings suggest that isolated dystonia may not be influenced by common genetic variations, highlighting the need for more extensive studies like whole-genome sequencing to uncover potential genetic contributions.
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Transition metal dichalcogenide heterostructures have garnered strong interest for their robust excitonic properties, mixed light-matter states such as exciton-polaritons, and tailored properties, vital for advanced device engineering. Two-dimensional heterostructures inherit their physics from monolayers with the addition of interlayer processes that have been particularly emphasized for their electronic and optical properties. Here, we demonstrate the interlayer coupling of the MoSe phonons to WSe excitons in a WSe/MoSe heterostructure using resonant Raman scattering.

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Near-field optical microscopy and spectroscopy provide high-resolution imaging below the diffraction limit, crucial in physics, chemistry, and biology for studying molecules, nanoparticles, and viruses. These techniques use a sharp metallic tip of an atomic force microscope (AFM) to enhance incoming and scattered light by excited near-fields at the tip apex, leading to high sensitivity and a spatial resolution of a few nanometers. However, this restricts the near-field orientation to out-of-plane polarization, limiting optical polarization choices.

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Objective: The SafetyCrown workflow facilitates the immediate restoration of posterior single sites with the one-abutment/one-time concept. This randomized clinical trial aimed to assess the direct effect of immediate restoration on dental patient-reported outcomes (dPROs), feasibility, implant accuracy, and time.

Materials And Methods: Participants with a single posterior edentulous site for late implant placement underwent optical impressions, shade selection, and cone beam computed tomography.

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Article Synopsis
  • Telescopic crown-retained dentures (TCDs) are widely used prosthetics for patients with missing teeth, but using a post and core (PC) treatment as an abutment often leads to failures, particularly due to fractures caused by extra axial forces.* -
  • A study analyzed 246 patients and 399 PC treatments over up to 17.33 years, comparing two scenarios: PC treatment performed at the time of TCD fitting (PC1) versus after an abutment tooth fracture (PC2).* -
  • Results indicated that PC2 had significantly lower survival rates than PC1, highlighting the importance of using PC1 when treating endodontically treated abutment teeth and the need for careful
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Bacteriocins are ribosomally synthesized peptides with the innate ability to kill or inhibit growth of other bacteria. In recent years, bacteriocins have received increased interest, as their antimicrobial activity enhances food safety and shelf life by combatting pathogens such as Listeria monocytogenes. They also have application potential as an active pharmaceutical compound to combat multidrug-resistant pathogens.

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Ordered arrays of plasmonic nanoparticles, supercrystals can lead to the formation of plasmon-polaritons. Coupling light emitters with plasmon polaritons might allow the formation of exciton-plasmon polaritons with properties tuneable by the supercrystal design. To construct such optically active materials, the inclusion of emitters is imperative.

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Recent advancements in materials science have shed light on the potential of exploring hierarchical assemblies of molecules on surfaces, driven by both fundamental and applicative challenges. This field encompasses diverse areas including molecular storage, drug delivery, catalysis, and nanoscale chemical reactions. In this context, the utilization of nanotube templates (NTs) has emerged as promising platforms for achieving advanced one-dimensional (1D) molecular assemblies.

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Dielectric screening plays a vital role in determining physical properties at the nanoscale and affects our ability to detect and characterize nanomaterials using optical techniques. We study how dielectric screening changes electromagnetic fields and many-body effects in nanostructures encapsulated inside carbon nanotubes. First, we show that metallic outer walls reduce the scattering intensity of the inner tube by 2 orders of magnitude compared to that of air-suspended inner tubes, in line with our local field calculations.

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