Publications by authors named "Rehan Razzaq"
Article Synopsis
- The study investigates how type 2 diabetes mellitus (T2DM) affects patients with end-stage liver disease who are on a liver transplantation waiting list.
- It includes 593 adult patients registered for liver transplant between 2010 and 2017 and assesses various clinical outcomes over a year, such as hospitalizations and the likelihood of receiving a transplant.
- Results indicate that patients with T2DM experience worse clinical outcomes, such as a higher risk of complications and lower chances of receiving a liver transplant, suggesting that the MELD score may not adequately reflect these risks.
Vibration-Controlled Transient Elastography-Based Parameters Predict Clinical Outcomes in Liver Transplant Recipients.
Clin Gastroenterol Hepatol
December 2024
Background And Aims: Vibration-controlled transient elastography (VCTE) is used in clinical practice to risk-stratify liver transplant (LT) recipients; however, there are currently little data demonstrating the relationship between VCTE and clinical outcomes.
Methods: A total of 362 adult LT recipients with successful VCTE examination between 2015 and 2022 were included. Presence of advanced fibrosis was defined as liver stiffness measurement (LSM) ≥10.
Precisely controlled synaptic glutamate concentration is essential for the normal function of the N-methyl D-aspartate (NMDA) receptors. Atypical fluctuations in synaptic glutamate homeostasis lead to aberrant NMDA receptor activity that results in the pathogenesis of neurological and psychiatric disorders. Therefore, glutamate concentration-dependent NMDA receptor modulators would be clinically useful agents with fewer on-target adverse effects.
View Article and Find Full Text PDF