Association of adipokines with obesity in children and adolescents.

Background: Childhood obesity is a global epidemic and is associated with a higher risk of chronic diseases such as hypertension, diabetes mellitus and other metabolic disorders. Several adipokines including resistin, visfatin, leptin and adiponectin are synthesized and secreted by adipocytes, which play an important role in obesity.

Patients & Methods: A total of 90 subjects (60 controls and 30 obese) between the ages of 5 and 18 years were selected.

Circulating leptin levels in elderly subjects with and without cerebrovasular disease.

Serum concentrations of leptin was investigated in 40 patients with ischemic stroke, in context of the size of the lesion and also in 40 non-diseased controls, matched according to age, gender and waist hip ratio. Serum leptin concentrations were determined in ng/ml with ELISA and computer tomography (CT) scan was performed in patients to estimate lesion size in cms. Serum leptin concentrations were found to be significantly higher (p < 0.

Pattern of perfusion defects seen in ischemic heart disease patients on technetium (Tc99m) tetrofosmin scanning.

Background: Cardiovascular disease is common cause of death in developed as well as developing countries. The most common cause of Ischemic Heart disease is narrowing of coronary arteries, a process called as atherosclerosis. The objective of the present study is to determine the pattern of ischemic changes detected by technetium tetrofosmin (Tc99m).

Comparison of troponin T and enzyme levels in acute myocardial infarction and skeletal muscle injury.

Background: The objective of this study was to compare the levels of troponin T and enzymes levels in myocardial infarction and skeletal muscle injury.

Methods: This study was carried out at Basic Medical Sciences Institute, JPMC Karachi, Pakistan. Ninety subjects were selected.