Fibroblast growth factor 23 in children with or without heart failure: a prospective study.

Background: Elevated fibroblast growth factor 23 (FGF23) levels have been associated with mortality in adults with heart failure (HF), but data on FGF23 levels in paediatric HF are limited. In this prospective cohort study, we aimed to assess the prognostic value of FGF23 in children with chronic HF.

Methods: We prospectively enrolled 40 children with chronic HF and 20 matched healthy controls.