Synthesis, DFT, and biological evaluation of chalcone bearing pyrazoline ring against receptors.

Peptic ulcer disease (PUD), often caused by infection, is a prevalent gastrointestinal condition characterized by the erosion of the gastric or duodenal mucosal lining. adheres to gastric epithelial cells, secreting toxins and disrupting the stomach's defenses. relies on various receptors to establish infection, making these molecules attractive therapeutic targets.